ReviewThe American journal of case reports2018
Primary Colonic Angiosarcoma Seen in a Patient on Calcium Channel Blocker: A Case Report with Summary Analysis of 32 Other Cases from the Literature.
Review in The American journal of case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Angiosarcoma-related cerebral metastases: a systematic review of the literature.Neurosurgical review · 2020Pooled it
- Stenosing Ileal Angiosarcoma Presenting as Subocclusive Syndrome: A Rare Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Rectal Angiosarcoma: A Case Report Highlighting Multidisciplinary Strategies for Rare Malignancies.Reports (MDPI) · 2025Article
- Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review.Archives of Iranian medicine · 2024Review
- Primary angiosarcoma of the ascending colon diagnosed after the discovery of intraoral tumor.Clinical journal of gastroenterology · 2023Article
- Primary Colonic Epithelioid Angiosarcoma with Hepatic Metastasis: A Case Report.Taehan Yongsang Uihakhoe chi · 2022Article
- Review
- Multiple Primary Angiosarcomas of the Colon.Case reports in pathology · 2021Article
- Metastatic angiosarcoma of unknown primary site misdiagnosed as tuberculosis.Clinical case reports · 2020Article
- Angiosarcoma characterized by colonic polyps: A case report.Medicine · 2020Article
- Colonic Angiosarcoma Arising in Association with Amyloid Deposits.Case reports in gastrointestinal medicine · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Angiosarcoma is a rare malignant mesenchymal tumor of vascular endothelial cell origin. Its occurrence in the colorectal region is extremely rare. Only 32 cases of primary colorectal angiosarcoma are reported in the current literature. Angiosarcoma in association with calcium channel blocker has been rarely reported. We present such a case of a patient who had been on levamlodipine besylate, a calcium channel blocker, for over 10 years. CASE REPORT A 53-year-old female with hypertension presented with a fever, a dry cough, and hematochezia. Computed tomography (CT) scan and angiography demonstrated a 6-cm vascular mass in the ileocecal region. The clinical symptoms stopped soon after a right hemicolectomy. The histopathology with immunohistochemical studies confirmed the diagnosis of angiosarcoma. Three months after surgery, the patient had evidence of recurrence of the tumor, however, she no longer presented with a fever or a dry cough. The patient was receiving chemotherapy at the time of the report. CONCLUSIONS Colorectal angiosarcoma is a rare malignancy of endothelial origin with uncertain etiology and often has a poor prognosis. Angiosarcoma seen in a patient taking calcium channel blocker is rare but alarming. CT scan and angiography are helpful tools to raise the suspicion of the diagnosis. A definitive pathological diagnosis relies on histopathology with immunohistochemical stains of endothelial markers. Surgical resection is still the best choice of the different treatment options.
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