Evidence map›Paper›PMID 29511047›Full record

Trial reportMolecular & cellular proteomics : MCP2018

Christofer A Q Karlsson, Sofia Järnum, Lena Winstedt, Christian Kjellman, Lars Björck, Adam Linder, Johan A Malmström

Open access · hybridAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in Molecular & cellular proteomics : MCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Immunomodulating Enzymes fromMicroorganisms · 2024
    Review
  6. Article
  7. Immunoglobulin M-degrading enzyme ofFrontiers in immunology · 2023
    Article
  8. Pharmaceutics · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. The Journal of experimental medicine · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christofer A Q KarlssonFrom the ‡Lund University, Division of Infection Medicine, Department of Clinical Sciences, Solvegatan 19, BMC, Lund, 221 84 Lund, Sweden.ORCID 0000-0002-7099-0092
Sofia Järnum§Hansa Medical AB, Scheelevägen 22, 223 63 Lund, Sweden.
Lena Winstedt§Hansa Medical AB, Scheelevägen 22, 223 63 Lund, Sweden.
Christian Kjellman§Hansa Medical AB, Scheelevägen 22, 223 63 Lund, Sweden.
Lars BjörckFrom the ‡Lund University, Division of Infection Medicine, Department of Clinical Sciences, Solvegatan 19, BMC, Lund, 221 84 Lund, Sweden.
Adam LinderFrom the ‡Lund University, Division of Infection Medicine, Department of Clinical Sciences, Solvegatan 19, BMC, Lund, 221 84 Lund, Sweden.
Johan A MalmströmFrom the ‡Lund University, Division of Infection Medicine, Department of Clinical Sciences, Solvegatan 19, BMC, Lund, 221 84 Lund, Sweden; johan.malmstrom@med.lu.se.
Lund University · SEHansa Biopharma (Sweden) · SE

Funding

European Research Council 309831
6 · The paper itself

Abstract

Infectious diseases are characterized by a complex interplay between host and pathogen, but how these interactions impact the host proteome is unclear. Here we applied a combined mass spectrometry-based proteomics strategy to investigate how the human proteome is transiently modified by the pathogen

Indexed as

ProteomeStreptococcus pyogenesAdolescentAdultBacterial ProteinsHumansImmunoglobulin GMaleMass SpectrometryMiddle AgedProteolysisSepsisStreptococcal InfectionsYoung AdultBacterial ProteinsImmunoglobulin GMac-1-like protein, StreptococcusProteomeBacteriaInfectious diseaseMicrobiologyMultiple reaction monitoringProteases*Targeted mass spectrometry

Identifiers

PMID29511047
PMCPMC5986240
OpenAlexW2805709035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.