Evidence map›Paper›PMID 29511022›Full record

ArticleDevelopment (Cambridge, England)2018

L(3)mbt and the LINT complex safeguard cellular identity in the

Rémi-Xavier Coux, Felipe Karam Teixeira, Ruth Lehmann

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Life science alliance · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Genes & development · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Germ granules in Drosophila.Traffic (Copenhagen, Denmark) · 2019
    Review
  15. Article
  16. Generating and working with Drosophila cell cultures: Current challenges and opportunities.Wiley interdisciplinary reviews. Developmental biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Rémi-Xavier CouxHoward Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6114-2585
Felipe Karam TeixeiraHoward Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-7651-1657
Ruth LehmannHoward Hughes Medical Institute (HHMI) and Kimmel Center for Biology and Medicine of the Skirball Institute, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA lehmann@saturn.med.nyu.edu.ORCID 0000-0002-8454-5651
Howard Hughes Medical Institute · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Germ Cell Migration in Drosophila.R37HD041900 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LEHMANN, RUTH · 2013 to 2021
$2.6M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA016087NICHD NIH HHS R37 HD041900NIH HHS P40 OD018537Wellcome TrustWellcome Trust 206257/Z/17/Z
6 · The paper itself

Abstract

Maintenance of cellular identity is essential for tissue development and homeostasis. At the molecular level, cell identity is determined by the coordinated activation and repression of defined sets of genes. The tumor suppressor L(3)mbt has been shown to secure cellular identity in

Indexed as

AnimalsCell DifferentiationDrosophilaDrosophila ProteinsFemaleFluorescent Antibody TechniqueGene Expression Regulation, DevelopmentalIn Situ Hybridization, FluorescenceLarvaOvaryRNA-Binding ProteinsSequence Analysis, RNADrosophila Proteinsl(3)mbt protein, Drosophilanos protein, DrosophilaRNA-Binding ProteinsDrosophilaL(3)mbtLint-1NanosOogenesisTissue identity

Identifiers

PMID29511022
PMCPMC5963868
OpenAlexW2793067790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.