Evidence map›Paper›PMID 29510884›Full record

ArticleDiagnostic microbiology and infectious disease2018

Evaluation of a real-time PCR assay for detection of Mycoplasma genitalium and macrolide resistance-mediating mutations from clinical specimens.

Li Xiao, Ken B Waites, Hong Wang, Barbara Van Der Pol, Amy E Ratliff, William M Geisler

Abstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. AutomatedMicrobiology spectrum · 2025
    Article
  3. Review
  4. Prevalence of Mycoplasma genitalium infection and macrolide resistance in pregnant women receiving prenatal care.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Article
  5. Article
  6. Frontiers in microbiology · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Li XiaoDepartment of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: lixiao@uabmc.edu.
Ken B WaitesDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: kwaites@uabmc.edu.
Hong WangDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: hwang@uab.edu.
Barbara Van Der PolDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: bvanderpol@uabmc.edu.
Amy E RatliffDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: amyratliff@uabmc.edu.
William M GeislerDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: wgeisler@uabmc.edu.
University of Alabama at Birmingham · US

Funding

The UAB Sexually Transmitted Infections Cooperative Research Centers (STI CRC)U19AI113212 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GEISLER, WILLIAM M · 2014 to 2018
$10.0M
NIAID NIH HHS U19 AI113212
6 · The paper itself

Abstract

Mycoplasma genitalium (MG) is a sexually transmitted pathogen for which there is no FDA-approved diagnostic test available in the United States. A modified real-time polymerase chain reaction assay for detecting MG and simultaneously identifying macrolide resistance mutations from clinical specimens was evaluated and proved to be sensitive and accurate for diagnostic purposes.

Indexed as

Mycoplasma genitaliumAnti-Bacterial AgentsDNA, BacterialDrug Resistance, BacterialHumansMacrolidesMutationMycoplasma InfectionsReal-Time Polymerase Chain ReactionReproducibility of ResultsSensitivity and SpecificityAnti-Bacterial AgentsDNA, BacterialMacrolidesMacrolideMycoplasma genitaliumReal-time PCRResistance

Identifiers

PMID29510884
PMCPMC5970045
OpenAlexW2787556426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.