Evidence map›Paper›PMID 29510749›Full record

ReviewParasites & vectors2018

Control of Lyme borreliosis and other Ixodes ricinus-borne diseases.

Hein Sprong, Tal Azagi, Dieuwertje Hoornstra, Ard M Nijhof, Sarah Knorr, M Ewoud Baarsma, Joppe W Hovius

Open access · goldAbstract readReview
In one paragraph

Review in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 3 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 3 syntheses or guidelines pooled it, 169 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026
    Review
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  9. Article
  10. Review
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  18. Deep sequencing of 16mSystems · 2025
    Article
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  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hein SprongCentre for Zoonoses & Environmental Microbiology, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands. hsprong@gmail.com.
Tal AzagiCentre for Zoonoses & Environmental Microbiology, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Dieuwertje HoornstraCenter for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
Ard M NijhofInstitute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Sarah KnorrInstitute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
M Ewoud BaarsmaCenter for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
Joppe W HoviusCenter for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
Academic Medical Center · NLFreie Universität Berlin · DENational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme borreliosis (LB) and other Ixodes ricinus-borne diseases (TBDs) are diseases that emerge from interactions of humans and domestic animals with infected ticks in nature. Nature, environmental and health policies at (inter)national and local levels affect the risk, disease burden and costs of TBDs. Knowledge on ticks, their pathogens and the diseases they cause have been increasing, and resulted in the discovery of a diversity of control options, which often are not highly effective on their own. Control strategies involving concerted actions from human and animal health sectors as well as from nature managers have not been formulated, let alone implemented. Control of TBDs asks for a "health in all policies" approach, both at the (inter)national level, but also at local levels. For example, wildlife protection and creating urban green spaces are important for animal and human well-being, but may increase the risk of TBDs. In contrast, culling or fencing out deer decreases the risk for TBDs under specific conditions, but may have adverse effects on biodiversity or may be societally unacceptable. Therefore, in the end, nature and health workers together must carry out tailor-made control options for the control of TBDs for humans and animals, with minimal effects on the environment. In that regard, multidisciplinary approaches in environmental, but also medical settings are needed. To facilitate this, communication and collaboration between experts from different fields, which may include patient representatives, should be promoted.

Indexed as

AnimalsCommunicable Disease ControlCost of IllnessEncephalitis, Tick-BorneHumansIxodesLyme DiseaseAnaplasmosisIxodes ricinusLyme borreliosisPreventionTick-borne encephalitisTransmission cyclesVaccines

Identifiers

PMID29510749
PMCPMC5840726
OpenAlexW2789951315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.