Evidence map›Paper›PMID 29510735›Full record

ArticleTrials2018

Comparative Efficacy and Mechanisms of a Single-Session Pain Psychology Class in Chronic Low Back Pain: Study Protocol for a Randomized Controlled Trial.

Beth D Darnall, Maisa S Ziadni, Anuradha Roy, Ming-Chih Kao, John A Sturgeon, Karon F Cook, Kate Lorig, John W Burns, Sean C Mackey

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03167086 ("Empowered Relief" Single Session Pain Psychology Treatment), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03167086 nacompletednot on this map

"Empowered Relief" Single Session Pain Psychology Treatment: Comparative Efficacy & Mechanisms

TypeinterventionalSponsorStanford UniversityRan2017 to 2020Enrolled263ConditionsChronic Low Back PainArms"Empowered Relief" (ER), Cognitive Behavioral Therapy (CBT), Health Education (HE)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beth D DarnallDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA. bdarnall@stanford.edu.
Maisa S ZiadniDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.
Anuradha RoyDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.
Ming-Chih KaoDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.
John A SturgeonDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.
Karon F CookFeinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Kate LorigDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.
John W BurnsDepartment of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.
Sean C MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford Systems Neuroscience and Pain Lab, 1070 Arastradero Road, Suite 200, MC 5596, Palo Alto, CA, 94304, USA.

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Single Session Pain Catastrophizing Treatment: Comparative Efficacy & MechanismsR01AT008561 · NCCIH · STANFORD UNIVERSITY · PI DARNALL, BETH DENISE, MACKEY, SEAN C · 2015 to 2019
$3.9M
Neuroimaging and Mentoring in Translational Pain ResearchK24DA029262 · NIDA · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2010 to 2019
$1.9M
NCCIH NIH HHS R01 AT008561NIDA NIH HHS 5K24DA029262-07NIDA NIH HHS K24 DA029262NIDA NIH HHS NIH T32 035165NIH HHS NIH R01 AT008561
6 · The paper itself

Abstract

backgroundThe Institute of Medicine (IOM) reported that chronic pain affects about 100 million U.S. adults, with chronic low back pain (CLBP) cited as the most prevalent type. Pain catastrophizing is a psychological construct shown to predict the development and trajectory of chronic pain and patient response to pain treatments. While effective treatment for pain catastrophizing typically includes eight-session groups of cognitive behavioral therapy (CBT), a single-session targeted treatment class yielded promising results which, if replicated and extended, could prove to efficiently and cost-effectively reduce pain catastrophizing. In this trial, we seek to determine the comparative efficacy of this novel single-session pain catastrophizing class to an eight-session course of pain CBT and a single-session back pain health education class. We will also explore the psychosocial mechanisms and outcomes of pain catastrophizing treatment.

methodsIn this trial we will randomize 231 individuals with CLBP to one of three treatment arms: (1) pain-CBT (eight weekly 2-h group sessions with home exercises and readings); (2) a single 2-h pain catastrophizing class; or (3) a single 2-h back pain health education class (active control). For the primary outcome of pain catastrophizing, the trial is designed as a non-inferiority test between pain-CBT and the single-session pain catastrophizing class, and as a superiority test between the single-session pain catastrophizing class and the health education class. Team researchers masked to treatment assignment will assess outcomes up to six months post treatment. DISCUSSION: If the single-session targeted pain catastrophizing class is found to be an effective treatment for patients with CLBP, this low cost and low burden treatment could dismantle many of the current barriers and burdens of effective pain care. Further, elucidation of the mechanisms of pain catastrophizing treatments will facilitate future research on the topic as well as further development and refinement of treatments.

trial registrationClinicalTrials.gov, NCT03167086 . Registered on 22 May 2017.

Indexed as

Cognitive Behavioral TherapyAdolescentAdultAgedCaliforniaCatastrophizationChronic PainComparative Effectiveness ResearchEquivalence Trials as TopicFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansLow Back PainMaleMiddle AgedBack painChronic painCognitive behavioral therapyPain catastrophizingPsychologyTreatment

Identifiers

PMID29510735
PMCPMC5838852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.