Evidence map›Paper›PMID 29510487›Full record

ArticleMolecules (Basel, Switzerland)2018

Quality Evaluation of Apocyni Veneti Folium from Different Habitats and Commercial Herbs Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical Analysis.

Cuihua Chen, Zixiu Liu, Lisi Zou, Xunhong Liu, Chuan Chai, Hui Zhao, Ying Yan, Chengcheng Wang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Total Flavonoids ofNutrients · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Quality Evaluation of Wild and CultivatedMolecules (Basel, Switzerland) · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cuihua ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. cuihuachen2013@163.com.ORCID 0000-0001-7722-2160
Zixiu LiuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. liuzixiu3221@126.com.
Lisi ZouCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. zlstcm@126.com.
Xunhong LiuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. liuxunh1959@163.com.
Chuan ChaiCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. echo_0523@hotmail.com.
Hui ZhaoCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. zhaohui_199301@163.com.
Ying YanCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. yanying93ly@163.com.
Chengcheng WangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. ccw199192@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apocyni Veneti Folium (AVF) is a kind of staple traditional Chinese medicine with vast clinical consumption because of its positive effects. However, due to the habitats and adulterants, its quality is uneven. To control the quality of this medicinal herb, in this study, the quality of AVF was evaluated based on simultaneous determination of multiple bioactive constituents combined with multivariate statistical analysis. A reliable method based on ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC-QTRAP-MS/MS) was developed for the simultaneous determination of a total of 43 constituents, including 15 flavonoids, 6 organic acids, 13 amino acids, and 9 nucleosides in 41 Luobumaye samples from different habitats and commercial herbs. Furthermore, according to the contents of these 43 constituents, principal component analysis (PCA) was employed to classify and distinguish between AVF and its adulterants, leaves of

Indexed as

Amino AcidsApocynumCarboxylic AcidsChromatography, High Pressure LiquidDrugs, Chinese HerbalFlavonoidsHumansMedicine, Chinese TraditionalMultivariate AnalysisNucleosidesPlant ExtractsPlant LeavesPrincipal Component AnalysisQuality ControlTandem Mass SpectrometryAmino AcidsCarboxylic AcidsDrugs, Chinese HerbalFlavonoidsNucleosidesPlant ExtractsApocyni Veneti Foliummultiple bioactive constituentsmultivariate statistical analysissimultaneous determinationUFLC-QTRAP-MS/MS

Identifiers

PMID29510487
PMCPMC6017895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.