Evidence map›Paper›PMID 29510112›Full record

ArticleCurrent biology : CB2018

Systems Neuroscience: The Exciting Journey to Oblivion.

George A Mashour, Max B Kelz

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Can Intraoperative Low-DoseFrontiers in pharmacology · 2020
    Review
  6. Sleep science in anesthesiology.Journal of anesthesia · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

George A MashourDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA; Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: gmashour@umich.edu.
Max B KelzCenter for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Funding

Medical Research Council G0901892
6 · The paper itself

Abstract

The mechanisms of anesthetic-induced unconsciousness remain incompletely understood. A recent study reveals that activation of glutamatergic neurons in the lateral habenula plays a causal role in general anesthesia. We explore the systems neuroscience implications of this finding.

Indexed as

AnesthesiaHabenulaNeurosciencesPropofolNeuronsPropofol

Identifiers

PMID29510112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.