ArticlePlant biotechnology journal2018
Seed-specific RNAi in safflower generates a superhigh oleic oil with extended oxidative stability.
Article in Plant biotechnology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 58 citations in OpenAlex.
- Integrative GWAS and transcriptomic analyses identify candidate genes associated with oil content and fatty acid composition in safflower.BMC plant biology · 2026Article
- Comparative Study of Fatty Acid Desaturase (FAD) Members Reveals Their Differential Roles in Upland Cotton.Plants (Basel, Switzerland) · 2025Article
- Genome-wide identification, characterization and expression analysis of WRKY transcription factors under abiotic stresses in Carthamus tinctorius L.BMC plant biology · 2025Article
- Integrated Proteomics and Metabolomics of Safflower Petal Wilting and Seed Development.Biomolecules · 2024Article
- Selection of Flax Genotypes for Pan-Genomic Studies by Sequencing Tagmentation-Based Transcriptome Libraries.Plants (Basel, Switzerland) · 2023Article
- KeyInternational journal of molecular sciences · 2023Article
- Improving the Technology of Primary Purification of the Safflower Oil Using Secondary Products of Processing on a Biological Basis.Foods (Basel, Switzerland) · 2023Article
- Bioengineering of Soybean Oil and Its Impact on Agronomic Traits.International journal of molecular sciences · 2023Review
- Genome-wide association studies dissect the G × E interaction for agronomic traits in a worldwide collection of safflowers (Molecular breeding : new strategies in plant improvement · 2022Article
- Development of a High Oleic Cardoon Cell Culture Platform byFrontiers in plant science · 2022Article
- Molecular Approaches Reduce Saturates and EliminateFrontiers in plant science · 2022Review
- Increasing Monounsaturated Fatty Acid Contents in HexaploidFrontiers in plant science · 2021Article
- Crop Quality Improvement Through Genome Editing Strategy.Frontiers in genome editing · 2021Review
- High-throughput phenotyping to dissect genotypic differences in safflower for drought tolerance.PloS one · 2021Article
- Digital Phenotyping to Delineate Salinity Response in Safflower Genotypes.Frontiers in plant science · 2021Article
- A Vernalization Response in a Winter Safflower (Frontiers in plant science · 2021Article
- The biochemistry of headgroup exchange during triacylglycerol synthesis in canola.The Plant journal : for cell and molecular biology · 2020Article
- Reorganization of Acyl Flux through the Lipid Metabolic Network in Oil-Accumulating Tobacco Leaves.Plant physiology · 2020Article
- Isolation and characterization of a novel seed-specific promoter from peanut (Arachis hypogaea L.).Molecular biology reports · 2019Article
- Estimation of crop plant density at early mixed growth stages using UAV imagery.Plant methods · 2019Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
Vegetable oils extracted from oilseeds are an important component of foods, but are also used in a range of high value oleochemical applications. Despite being biodegradable, nontoxic and renewable current plant oils suffer from the presence of residual polyunsaturated fatty acids that are prone to free radical formation that limit their oxidative stability, and consequently shelf life and functionality. Many decades of plant breeding have been successful in raising the oleic content to ~90%, but have come at the expense of overall field performance, including poor yields. Here, we engineer superhigh oleic (SHO) safflower producing a seed oil with 93% oleic generated from seed produced in multisite field trials spanning five generations. SHO safflower oil is the result of seed-specific hairpin-based RNA interference of two safflower lipid biosynthetic genes, FAD2.2 and FATB, producing seed oil containing less than 1.5% polyunsaturates and only 4% saturates but with no impact on lipid profiles of leaves and roots. Transgenic SHO events were compared to non-GM safflower in multisite trial plots with a wide range of growing season conditions, which showed no evidence of impact on seed yield. The oxidative stability of the field-grown SHO oil produced from various sites was 50 h at 110°C compared to 13 h for conventional ~80% oleic safflower oils. SHO safflower produces a uniquely stable vegetable oil across different field conditions that can provide the scale of production that is required for meeting the global demands for high stability oils in food and the oleochemical industry.
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Registered trials
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