Evidence map›Paper›PMID 29509680›Full record

ArticleMolecules (Basel, Switzerland)2018

[

Teresa Mann, Jens Kurth, Alexander Hawlitschka, Jan Stenzel, Tobias Lindner, Stefan Polei, Alexander Hohn, Bernd J Krause, Andreas Wree

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Olfactory Bulb DToxins · 2022
    Article
  7. Article
  8. Experimental Intrastriatal Applications of Botulinum Neurotoxin-A: A Review.International journal of molecular sciences · 2018
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Teresa MannInstitute of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany. teresa.mann@med.uni-rostock.de.
Jens KurthDepartment of Nuclear Medicine, Rostock University Medical Centre, Gertrudenplatz 1, 18057 Rostock, Germany. jens.kurth@med.uni-rostock.de.ORCID 0000-0001-6864-4513
Alexander HawlitschkaInstitute of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany. alexander.hawlitschka@med.uni-rostock.de.
Jan StenzelCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Schillingallee 69a, 18057 Rostock, Germany. Jan.Stenzel@med.uni-rostock.de.
Tobias LindnerCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Schillingallee 69a, 18057 Rostock, Germany. tobias.lindner@med.uni-rostock.de.ORCID 0000-0001-7826-3132
Stefan PoleiCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Schillingallee 69a, 18057 Rostock, Germany. stefan.polei@gmx.de.
Alexander HohnDepartment of Nuclear Medicine, Rostock University Medical Centre, Gertrudenplatz 1, 18057 Rostock, Germany. alexander.hohn@med.uni-rostock.de.
Bernd J KrauseDepartment of Nuclear Medicine, Rostock University Medical Centre, Gertrudenplatz 1, 18057 Rostock, Germany. bernd.krause@med.uni-rostock.de.
Andreas WreeInstitute of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany. andreas.wree@med.uni-rostock.de.
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrastriatal injection of botulinum neurotoxin A (BoNT-A) results in improved motor behavior of hemiparkinsonian (hemi-PD) rats, an animal model for Parkinson's disease. The caudate-putamen (CPu), as the main input nucleus of the basal ganglia loop, is fundamentally involved in motor function and directly interacts with the dopaminergic system. To determine receptor-mediated explanations for the BoNT-A effect, we analyzed the dopamine D₂/D₃ receptor (D₂/D₃R) in the CPu of 6-hydroxydopamine (6-OHDA)-induced hemi-PD rats by [

Indexed as

Brain ChemistryAnimalsBehavior, AnimalBenzamidesBotulinum Toxins, Type AInjectionsMaleParkinsonian DisordersPositron Emission Tomography Computed TomographyPyrrolidinesRatsRats, WistarReceptors, Dopamine D2Receptors, Dopamine D3BenzamidesBotulinum Toxins, Type AN-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2,3-dimethoxybenzamidePyrrolidinesReceptors, Dopamine D2Receptors, Dopamine D3[18F]fallypridebasal gangliaBotulinum neurotoxin AD2/D3 receptorshemiparkinsonian rat modelMRIParkinson’s diseasePET/CTsmall animal imagingstriatum

Identifiers

PMID29509680
PMCPMC6017015
OpenAlexW2791984602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.