Evidence map›Paper›PMID 29509587›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Cango Lyec (Healing the Elephant): Gender Differences in HIV Infection in Post-conflict Northern Uganda.

Patricia M Spittal, Samuel S Malamba, Martin D Ogwang, Seggane Musisi, J Paul Ekwaru, Nelson K Sewankambo, Margo E Pearce, Kate Jongbloed, Sheetal H Patel, Achilles Katamba and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Ethical Principles and Practices in HIV Acquisition Research in Humanitarian Crises: A Cross-Sectional Study.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Patricia M SpittalSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Samuel S MalambaUganda Virus Research Institute, Entebbe, Uganda.
Martin D OgwangSt. Mary's Lacor Hospital, Gulu, Uganda.
Seggane MusisiCollege of Health Sciences, Makerere University, Kampala, Uganda.
J Paul EkwaruSchool of Public Health, University of Alberta, Edmonton, Canada.
Nelson K SewankamboCollege of Health Sciences, Makerere University, Kampala, Uganda.
Margo E PearceCanadian HIV Trials Network, Vancouver, Canada.
Kate JongbloedSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Sheetal H PatelBC Children's Hospital Research Institute, Vancouver, Canada.
Achilles KatambaCollege of Health Sciences, Makerere University, Kampala, Uganda.
Alden H BlairSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Herbert MuyindaCollege of Health Sciences, Makerere University, Kampala, Uganda.
Martin T SchechterSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Makerere University · UGUniversity of British Columbia · CABC Children's Hospital · CAHIV Legal Network · CASt. Mary's Hospital Lacor · UGUganda Virus Research Institute · UGUniversity of Alberta · CA

Funding

CIHR
6 · The paper itself

Abstract

backgroundAs previously encamped resettle, potential for rapid HIV transmission in post-conflict Northern Uganda is concerning. Women in particular may be experiencing heightened vulnerability resulting from war-related sexual violence.

settingCango Lyec (Healing the Elephant) Project is a cohort involving conflict-affected people in 3 districts in Northern Uganda.

methodsEight randomly selected communities were mapped, and a census was conducted. Participants aged 13-49 years completed questionnaires in Luo on war-related experiences, mental health, sexual vulnerabilities, and sociodemographics. Blood samples were tested for HIV and syphilis. Baseline data from all sexually active participants was used to determine gender differences in HIV prevalence. Multivariate modeling determined correlates of HIV by gender.

resultsAmong 2008 participants, HIV prevalence was higher among women [17.2; 95% confidence interval (CI): 14.7 to 19.7] compared to men (10.6; 95% CI: 8.0 to 13.2, <0.001). Among women, correlates of HIV included: war-related sexual assault [adjusted odds ratio (AOR): 1.95; 95% CI: 1.16 to 3.26]; probable depression (AOR: 2.22; 95% CI: 1.46 to 3.37); probable post-traumatic stress disorder (AOR: 2.03; 95% CI: 1.45 to 2.84); experiencing ≥12 traumatic events (AOR: 2.04; 95% CI: 1.31 to 3.18); suicide ideation (AOR: 1.67; 95% CI: 1.22 to 2.28); living in a female-headed household (AOR: 2.76; 95% CI: 1.70 to 4.49); first sexual partner ≥10 years older (AOR: 1.69; 95% CI: 1.07 to 2.67); sex for exchange (AOR: 5.51; 95% CI: 1.76 to 17.31); having 2 (AOR: 2.54; 95% CI: 1.23 to 5.23) or 3+ (AOR: 4.65; 95% CI: 2.65 to 8.18) sexual partners; inconsistent condom use (AOR: 0.40; 95% CI: 0.29 to 0.57); genital ulcers (AOR: 3.08; 95% CI: 2.16 to 4.38); active syphilis (AOR: 4.33; 95% CI: 1.22 to 15.40); and ill health without medical care (AOR: 2.02; 95% CI: 1.22 to 3.34). Among men, correlates of HIV included no condom at sexual debut (AOR: 1.92; 95% CI: 1.30 to 2.83) and genital ulcers (AOR: 4.40; 95% CI: 1.35 to 14.40).

conclusionWomen are disproportionately impacted by HIV, trauma, and depression in this conflict-affected population. Trauma-informed HIV prevention and culturally safe mental health initiatives are urgently required.

Indexed as

Armed ConflictsSex FactorsAdolescentAdultDepressionFemaleHIV InfectionsHIV SeroprevalenceHumansMaleMiddle AgedRapeStress Disorders, Post-TraumaticSurveys and QuestionnairesUgandaYoung Adult

Identifiers

PMID29509587
PMCPMC6012052
OpenAlexW2793440012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.