ArticleBioEssays : news and reviews in molecular, cellular and developmental biology2018
Active Sleep Promotes Functional Connectivity in Developing Sensorimotor Networks.
Article in BioEssays : news and reviews in molecular, cellular and developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep and prematurity: sleep outcomes in preterm children and influencing factors.World journal of pediatrics : WJP · 2019Pooled it
- Changes of cerebral functional connectivity induced by foot reflexology in a RCT.Scientific reports · 2023Trial
- Skin-to-skin contact improves sleep stability in preterm infants.Pediatric research · 2026Article
- Characterization of aperiodic and theta activity in preterm infants using EEG: Insights into cerebral maturation and inter-individual variability.Developmental cognitive neuroscience · 2026Article
- Twitching in sleeping premature infants provides a sensitive behavioral assay of early motor control.iScience · 2026Article
- Sleep During NICU Care Is Associated With Proportional Cerebellar Size at Term-Equivalent Age in Extrem Infantsmely Preter.Cerebellum (London, England) · 2026Article
- Twitching in sleeping premature infants provides a sensitive behavioral assay of early motor control.bioRxiv : the preprint server for biology · 2026Article
- Sleep state-dependent development of resting-state functional connectivity during the preterm period.Sleep · 2024Article
- Sleep as a driver of pre- and postnatal brain development.Pediatric research · 2024Review
- Knowledge mapping of neonatal electroencephalogram: A bibliometric analysis (2004-2022).Brain and behavior · 2024Article
- Machine Learning-Derived Active Sleep as an Early Predictor of White Matter Development in Preterm Infants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Early-life maturation of the somatosensory cortex: sensory experience and beyond.Frontiers in neural circuits · 2024Review
- Article
- Axonal connections between S1 barrel, M1, and S2 cortex in the newborn mouse.Frontiers in neuroanatomy · 2023Article
- Article
- Comparison of the Effect of Nesting and Swaddling on Sleep Duration and Arousal Frequency among Preterm Neonates: A Randomized Clinical Trial.Journal of caring sciences · 2022Article
- Impact of In Utero Exposure to Antiepileptic Drugs on Neonatal Brain Function.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Neural correlates of sleep quality in children: Sex-specific associations shown by brain diffusion tractography.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms.Sleep medicine reviews · 2022Review
- Early development of sleep and brain functional connectivity in term-born and preterm infants.Pediatric research · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
A ubiquitous feature of active (REM) sleep in mammals and birds is its relative abundance in early development. In rat pups across the first two postnatal weeks, active sleep promotes the expression of synchronized oscillatory activity within and between cortical and subcortical sensorimotor structures. Sensory feedback from self-generated myoclonic twitches - which are produced exclusively during active sleep - also triggers neural oscillations in those structures. We have proposed that one of the functions of active sleep in early infancy is to provide a context for synchronizing developing structures. Specifically, neural oscillations contribute to a variety of neurodevelopmental processes, including synapse formation, neuronal differentiation and migration, apoptosis, and the refinement of topographic maps. In addition, synchronized oscillations promote functional connectivity between distant brain areas. Consequently, any condition or manipulation that restricts active sleep can, in turn, deprive the infant animal of substantial sensory experience, resulting in atypical developmental trajectories.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.