Evidence map›Paper›PMID 29508544›Full record

ArticleGenesis (New York, N.Y. : 2000)2018

Generation and characterization of Lhx3

Mei Xu, Xiaoling Xie, Xuhui Dong, Guoqing Liang, Lin Gan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genesis (New York, N.Y. : 2000), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Dwarfism in Tibetan Terrier dogs with anJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mei XuInstitute of Life Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, 310036, China.ORCID 0000-0002-2638-9232
Xiaoling XieDepartment of Ophthalmology and Flaum Eye Institute, University of Rochester, Rochester, New York, 14642.
Xuhui DongInstitute of Life Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, 310036, China.
Guoqing LiangInstitute of Life Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, 310036, China.
Lin GanDepartment of Ophthalmology and Flaum Eye Institute, University of Rochester, Rochester, New York, 14642.
Hangzhou Normal University · CNUniversity of Rochester · US

Funding

The Roles of LIM-Homeodomain Transcription Factors in Retinal DevelopmentR01EY026614 · NEI · UNIVERSITY OF ROCHESTER · PI GAN, LIN · 2016 to 2020
$1.9M
NEI NIH HHS R01 EY026614
6 · The paper itself

Abstract

LHX3, a LIM-homeodomain transcription factor, is broadly expressed in the developing pituitary, spinal cord, medulla, retina and inner ear, and plays essential roles during embryonic development. Mice with homozygous Lhx3 null mutation exhibit failure in the formation of pituitary gland and die perinatally. To facilitate the functional study of Lhx3 in mice, we engineered and characterized two novel Lhx3 mouse strains: Lhx3

Indexed as

AnimalsExonsGene Expression Regulation, DevelopmentalGenetic EngineeringHomeodomain ProteinsLIM-Homeodomain ProteinsMiceMice, KnockoutMutationPituitary GlandTranscription FactorsHomeodomain ProteinsLhx3 proteinLIM-Homeodomain ProteinsTranscription Factorsinner earLIM homeodomainpituitaryretinaspinal cordtranscription factor

Identifiers

PMID29508544
PMCPMC5908734
OpenAlexW2792190430

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.