ArticleInternational journal of colorectal disease2018
Loop-ileostomy reversal-patient-related characteristics influencing time to closure.
Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Superior anal function in patients undergoing stoma closure within 6 months after LAR and analysis of factors associated with LARS syndrome: insights from experienced surgeons.Updates in surgery · 2025Review
- Stoma reversal after emergency stoma formation-the importance of timing: a multi-centre retrospective cohort study.World journal of emergency surgery : WJES · 2025Article
- Impact of chemotherapy on surgical outcomes in ileostomy reversal: a propensity score matching study from a single centre.Techniques in coloproctology · 2023Article
- Impact of ileostomy in the adjuvant treatment and outcome of colon cancer.International journal of colorectal disease · 2023Observational
- The impact of postoperative complications severity on stoma reversal following sphincter-preserving surgery for rectal cancer.Langenbeck's archives of surgery · 2022Article
- Can physiological stimulation prior to ileostomy closure reduce postoperative ileus? A prospective multicenter pilot study.Techniques in coloproctology · 2022Article
- Ostomy closure rate during COVID-19 pandemic: an Italian multicentre observational study.Updates in surgery · 2022Observational
- Effects of ethnicity and socioeconomic status on surgical outcomes from inflammatory bowel disease.International journal of colorectal disease · 2022Observational
- Timing of Closure of a Protective Loop-Ileostomy Can Be Crucial for Restoration of a Functional Digestion.Frontiers in surgery · 2022Article
- Permanent stoma rates after anterior resection for rectal cancer: risk prediction scoring using preoperative variables.The British journal of surgery · 2021Article
- Impact of timing of reversal of loop ileostomy on patient outcomes: a retrospective cohort study.Techniques in coloproctology · 2021Article
- Article
- Multidisciplinary management of elderly patients with rectal cancer: recommendations from the SICG (Italian Society of Geriatric Surgery), SIFIPAC (Italian Society of Surgical Pathophysiology), SICE (Italian Society of Endoscopic Surgery and new technologies), and the WSES (World Society of Emergency Surgery) International Consensus Project.World journal of emergency surgery : WJES · 2021Article
- Early postoperative outcomes of diverting loop ileostomy closure surgery following laparoscopic versus open colorectal surgery.Surgical endoscopy · 2021Article
- Loop ileostomy in rectal cancer surgery: factors predicting reversal and stoma related morbidity.Langenbeck's archives of surgery · 2021Article
- Clinical Outcomes of Ileostomy Closure before Adjuvant Chemotherapy after Rectal Cancer Surgery: An Observational Study from a Chinese Center.Gastroenterology research and practice · 2021Article
- Stoma reversal after intended restorative rectal cancer resection in Denmark: nationwide population-based study.BJS open · 2020Article
- Assessment of the risk of permanent stoma after low anterior resection in rectal cancer patients.World journal of surgical oncology · 2020Article
- Neoadjuvant radiotherapy for rectal cancer management.World journal of gastroenterology · 2019Review
- Long distance to hospital is not a risk factor for non-reversal of a defunctioning stoma.International journal of colorectal disease · 2019Article
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Authors and funding
4 authors.
Funding
Abstract
purposeTo identify factors associated with timing of stoma reversal after rectal cancer surgery in a large Swedish register-based cohort.
methodsThree thousand five hundred sixty-four patients with rectal cancer who received a protective stoma during surgery in 2007-2013 were identified in the Swedish colorectal cancer register. Time to stoma reversal was evaluated over a follow-up period of one and a half years. Factors associated with timing of stoma reversal were analysed using Cox regression analysis. Reversal within 9 months (12 months if adjuvant chemotherapy) was considered latest expected time to closure.
resultsStoma reversal was performed in 2954 (82.9%) patients during follow-up. Patients with post-secondary education had an increased chance for early stoma reversal (HR 1.13; 95% CI 1.02-1.25). Postoperative complications (0.67; 0.62-0.73), adjuvant chemotherapy (0.63; 0.57-0.69), more advanced cancer stage (stage III 0.74; 0.66-0.83 and stage IV 0.38; 0.32-0.46) and higher ASA score (0.80; 0.71-0.90 for ASA 3-4) were associated with longer time to reversal. Two thousand four hundred thirty-seven (68.4%) patients had stoma reversal within latest expected time to closure. Factors associated to decreased chance of timely reversal were more advanced cancer stage (stage III 0.64; 0.50-0.81 and stage IV 0.19; 0.13-0.27), postoperative complications (0.50; 0.42-0.59) and higher ASA score (0.77; 0.61-0.96 for ASA 3-4).
conclusionsPatients with a high level of education had a higher chance of timely reversal but medical factors had a stronger association to time to reversal. Patients with advanced rectal cancer are at high risk for non-reversal and should be considered for permanent stoma.
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