ArticlePeerJ2018
Gender-associated factors for frailty and their impact on hospitalization and mortality among community-dwelling older adults: a cross-sectional population-based study.
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Cross-education of lower limb muscle strength following resistance exercise training in males and females: A systematic review and meta-analysis.Experimental physiology · 2026Pooled it
- Pooled it
- Healthcare resource utilization in patients treated with empagliflozin in East Asia.Journal of diabetes investigation · 2022Pooled it
- How wearable sensors have been utilised to evaluate frailty in older adults: a systematic review.Journal of neuroengineering and rehabilitation · 2021Pooled it
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- Trial
- Protein-Added Healthy Lunch-Boxes Combined with Exercise for Improving Physical Fitness and Vascular Function in Pre-Frail Older Women: A Community-Based Randomized Controlled Trial.Clinical interventions in aging · 2023Trial
- Sensory and motor correlates of frailty: dissociation between frailty phenotype and frailty index.BMC geriatrics · 2022Trial
- Latent classes of frailty and their association with intrinsic capacity inolder cancer survivors: A study under the healthy aging paradigm.Global health & medicine · 2026Article
- Explainable Machine Learning Approaches Predict Frailty and Adverse Outcomes in Older Adults: Development and Validation with Two Longitudinal Cohorts.Journal of clinical medicine · 2026Article
- Impact of frailty on balance, fall risk, and kinesiophobia in sarcopenic elderly.BMC geriatrics · 2025Article
- National Norms for Hospital Frailty Risk Score Among Hospitalized Adults in the USA.Journal of general internal medicine · 2025Article
- Prevalence and impact of frailty on unplanned hospitalizations among adult patients with cancer in Taiwan.The oncologist · 2025Article
- The Relationship Between Health-Related Quality of Life and Frailty in Older Patients Participating in Early Phase II Cardiac Rehabilitation.Circulation reports · 2025Article
- The impact of social participation on activities of daily living in older adults with knee osteoarthritis: the chain mediating effects of sleep quality and multidimensional frailty.Frontiers in psychology · 2025Article
- Article
- Caregiving burdens of task time and task difficulty among paid and unpaid caregivers of persons living with dementia.Frontiers in public health · 2025Article
- Association between frailty and pain in older people at high risk of future hospitalization.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- The Effect of Frailty on Balance, Fear of Falling, and Dual-Task Performance in Individuals with Type 2 DM.Life (Basel, Switzerland) · 2024Article
- Development and validation of machine learning-derived frailty index in predicting outcomes of patients undergoing percutaneous coronary intervention.International journal of cardiology. Heart & vasculature · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty associated with aging increases the risk of falls, disability, and death. We investigated gender-associated factors for frailty.
methodsData of 3,079 geriatric subjects were retrieved from the National Health and Nutrition Examination Survey (NHANES) 2007-2010 database. After excluding 1,126 subjects with missing data on frailty, medical history and survival, data of 1,953 patients were analyzed. Main endpoints were frailty prevalence, mortality rates and causes of death.
resultsFrailty prevalence was 5.4% in males, 8.8% in females. Significant risk factors for geriatric frailty in males were being widowed/divorced/separated, low daily total calorie intake, physical inactivity, sleeping >9 h, smoking and hospitalization history; and in females were obesity, physical inactivity, sleeping <6 h, family history of diabetes and heart attack, and hospitalization history. Frail subjects had higher mortality rates (22.5% male; 8.5% female) than pre-frail (8.7% male; 6.4% female) and non-frail (5.4% male; 2.5% female). Main causes of death were heart diseases (41%) and chronic lower respiratory diseases (23.0%) in males and nephritis/nephrosis (32.3%) and chronic lower respiratory diseases (17.6%) in females. DISCUSSION: Factors associated with frailty differ by gender, with higher frailty prevalence in females and higher mortality in males. Gender-associated factors for frailty identified in this study may be useful in evaluating frailty and guiding development of public health measures for prevention. KEY MESSAGE: Common predictive factors for frailty among older adults of both genders, including more frequent previous hospitalizations, physical inactivity, and certain gender-associated factors for frailty, are consistent with results of other NHANES studies in which self-reported higher levels of illness and sedentary behavior were directly associated with frailty.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.