ReviewMultidisciplinary respiratory medicine2018
The patient needing prolonged mechanical ventilation: a narrative review.
Review in Multidisciplinary respiratory medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Early versus late tracheostomy in people with multiple trauma.The Cochrane database of systematic reviews · 2025Pooled it
- Interventions to enable communication for adult patients requiring an artificial airway with or without mechanical ventilator support.The Cochrane database of systematic reviews · 2021Pooled it
- Joint Statement on the Role of Respiratory Rehabilitation in the COVID-19 Crisis: The Italian Position Paper.Respiration; international review of thoracic diseases · 2020Guideline
- Trial
- Effectiveness of a standardized weaning protocol in tracheostomized patients with prolonged mechanical ventilation: a prospective single-arm interventional trial.Journal of intensive care · 2026Article
- Multidisciplinary Rehabilitation for Severe Respiratory Failure Due to Dasatinib-Induced Pulmonary Toxicity: A Case Report.The American journal of case reports · 2026Article
- The Perspectives of Families in Decision-Making Conflicts Related to Palliative Care Patients With Mechanical Ventilation in Taiwan.The American journal of hospice & palliative care · 2026Article
- Prolonged mechanical ventilation and its associated factors among adult patients admitted to intensive care unit in the teaching hospitals of Southern Ethiopia In 2023: a multicenter prospective cohort study.BMC anesthesiology · 2026Article
- Prevalence, Clinical Characteristics, and Outcomes of Intensive Care Unit Patients Requiring Prolonged Mechanical Ventilation in a Tertiary Hospital in the Philippines: A Single-center Retrospective Cross-sectional Study.Acta medica Philippina · 2026Article
- [Impact of severe laryngotracheal injuries on decannulation failure in adult patients. Retrospective cohort]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Predictive value of the geriatric nutritional risk index for postoperative outcomes and healthcare costs in patients undergoing pancreaticoduodenectomy.Updates in surgery · 2025Article
- Effects of continuous mobility training versus hand bicycle exercise in individuals with prolonged mechanical ventilation: A randomized-controlled trial.Turkish journal of physical medicine and rehabilitation · 2025Article
- Article
- Influence of clinical severity and ventilation time on the use of timed inspiratory effort (TIE) as a predictor of success in ventilatory weaning.Journal of thoracic disease · 2025Article
- Prolonged T-Piece Spontaneous Breathing Trial and Extubation Outcomes in Patients Received Prolonged Mechanical Ventilation.Medicina (Kaunas, Lithuania) · 2025Article
- Multidisciplinary collaborative approach to cardiopulmonary rehabilitation in cancer patients with intensive care unit-acquired weakness: a clinical efficacy and safety analysis.American journal of cancer research · 2025Article
- Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices.Nanomaterials (Basel, Switzerland) · 2024Article
- Early versus late tracheostomy in people with multiple trauma.The Cochrane database of systematic reviews · 2024Article
- Impact of mechanical ventilation on clinical outcomes in ICU-admitted Alzheimer's disease patients: a retrospective cohort study.Frontiers in public health · 2024Article
- Post-extubation Assessment of Laryngeal Symptoms and Severity (PALSS) in the Intensive Care Unit: Protocol of a Prospective Cohort Study.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProgress in management has improved hospital mortality of patients admitted to the intensive care units, but also the prevalence of those patients needing weaning from prolonged mechanical ventilation, and of ventilator assisted individuals. The result is a number of difficult clinical and organizational problems for patients, caregivers and health services, as well as high human and financial resources consumption, despite poor long-term outcomes. An effort should be made to improve the management of these patients. This narrative review summarizes the main concepts in this field. MAIN BODY: There is great variability in terminology and definitions of prolonged mechanical ventilation.There have been several recent developments in the field of prolonged weaning: ventilatory strategies, use of protocols, early mobilisation and physiotherapy, specialised weaning units.There are few published data on discharge home rates, need of home mechanical ventilation, or long-term survival of these patients.Whether artificial nutritional support improves the outcome for these chronic critically ill patients, is unclear and controversial how these data are reported on the optimal time of initiation of parenteral vs enteral nutrition.There is no consensus on time of tracheostomy or decannulation. Despite several individualized, non-comparative and non-validated decannulation protocols exist, universally accepted protocols are lacking as well as randomised controlled trials on this critical issue. End of life decisions should result from appropriate communication among professionals, patients and surrogates and national legislations should give clear indications.
conclusionPresent medical training of clinicians and locations like traditional intensive care units do not appear enough to face the dramatic problems posed by these patients. The solutions cannot be reserved to professionals but must involve also families and all other stakeholders. Large multicentric, multinational studies on several aspects of management are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.