Evidence map›Paper›PMID 29507487›Full record

ArticleCurrent oncology (Toronto, Ont.)2018

Standardizing biomarker testing for Canadian patients with advanced lung cancer.

B Melosky, N Blais, P Cheema, C Couture, R Juergens, S Kamel-Reid, M-S Tsao, P Wheatley-Price, Z Xu, D N Ionescu

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

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  16. Canadian Consensus Recommendations on the Management ofCurrent oncology (Toronto, Ont.) · 2021
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  20. Optimizing management of advanced urothelial carcinoma: A review of emerging therapies and biomarker-driven patient selection.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

B MeloskyBritish Columbia Cancer Agency, Vancouver Centre, Vancouver BC.
N BlaisCHUM, Montreal, Quebec.
P CheemaWilliam Osler Health System, University of Toronto, Toronto, Ontario.
C CoutureIUCPQ-Université Laval, Québec City, Quebec.
R JuergensMcMaster University, Juravinski Cancer Centre, Hamilton, Ontario, Chair of Medical Advisory Committee, Lung Cancer Canada.
S Kamel-ReidUniversity Health Network, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario.
M-S TsaoUniversity Health Network, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario.
P Wheatley-PriceUniversity of Ottawa/Ottawa Hospital Research Institute; President Lung Cancer Canada.
Z XuQueen Elizabeth II Health Sciences Centre/Dalhousie University, Halifax NS.
D N IonescuBritish Columbia Cancer Agency, Vancouver Centre, Vancouver BC.
BC Cancer Agency · CAUniversity of Toronto · CACentre Hospitalier de l’Université de Montréal · CAInstitut Universitaire de Cardiologie et de Pneumologie de Québec · CAJuravinski Cancer Centre · CAOttawa Hospital Research InstituteQueen Elizabeth II Health Sciences Centre · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development and approval of both targeted and immune therapies for patients with advanced non-small cell lung cancer (nsclc) has significantly improved patient survival rates and quality of life. Biomarker testing for patients newly diagnosed with nsclc, as well as for patients progressing after treatment with epidermal growth factor receptor (

methodsA group of thoracic oncology experts in the field of thoracic oncology met to describe the standard for biomarker testing for lung cancer in the Canadian context, focusing on evidence-based recommendations for standard-of-care testing for

resultsThe standard of care must include the incorporation of testing for novel biomarkers as they become available, as it will be difficult for national guidelines to keep pace with technological advances in this area.

conclusionsCanadian patients with nsclc should be treated equally; the minimum standard of care is defined in this paper.

Indexed as

ALKBiomarker testingBRAF V600XCanadaEGFRlung cancerMETPD-L1ROS1

Identifiers

PMID29507487
PMCPMC5832280
OpenAlexW2789986687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.