Evidence map›Paper›PMID 29507364›Full record

ArticleScientific reports2018

Allogeneic dendritic cells stimulated with antibodies against HLA class II polarize naive T cells in a follicular helper phenotype.

Olivier Désy, Stéphanie Béland, Patrice Vallin, Julie Riopel, Eva Latulippe, Eric Wagner, Sacha A De Serres

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. CXCR5Frontiers in immunology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Olivier DésyTransplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Laval University, Québec, QC, Canada.
Stéphanie BélandTransplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Laval University, Québec, QC, Canada.
Patrice VallinTransplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Laval University, Québec, QC, Canada.ORCID 0000-0003-4758-6750
Julie RiopelDepartment of Pathology, University Health Center of Quebec, Laval University, Québec, QC, Canada.
Eva LatulippeDepartment of Pathology, University Health Center of Quebec, Laval University, Québec, QC, Canada.
Eric WagnerImmunology and Histocompatibility Laboratory, University Health Center of Quebec, Laval University, Québec, QC, Canada.
Sacha A De SerresTransplantation Unit, Renal Division, Department of Medicine, University Health Center of Quebec, Laval University, Québec, QC, Canada. sacha.deserres@crchuq.ulaval.ca.
Université Laval · CA

Funding

CIHR 201309CIHR KRI123890
6 · The paper itself

Abstract

Follicular helper T cells (Tfh) are crucial for the production of high-affinity antibodies, such as alloantibodies, by providing the signals for B-cell proliferation and differentiation. Here, we demonstrate that human allogeneic dendritic cells (DC) stimulated with antibodies against HLA class II antigens preferentially differentiate human naive CD4

Indexed as

Cells, CulturedDendritic CellsHistocompatibility Antigens Class IIHumansImmunophenotypingIsoantibodiesKidney TransplantationReceptors, CXCR5T-LymphocytesCXCR5 protein, humanHistocompatibility Antigens Class IIIsoantibodiesReceptors, CXCR5

Identifiers

PMID29507364
PMCPMC5838222
OpenAlexW2805168082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.