Evidence map›Paper›PMID 29507235›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Single-molecule analysis of phospholipid scrambling by TMEM16F.

Rikiya Watanabe, Takaharu Sakuragi, Hiroyuki Noji, Shigekazu Nagata

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
  2. Article
  3. Metabolic Control of Membrane Lipid Asymmetry in Cancer.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. A cell-based scrambling assay reveals the phospholipid headgroup preference of TMEM16F on the plasma membrane.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Lipid scrambling is a general feature of protein insertases.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rikiya WatanabeDepartment of Applied Chemistry, The University of Tokyo, Tokyo 113-8656, Japan; wrikiya@nojilab.t.u-tokyo.ac.jp hnoji@appchem.t.u-tokyo.ac.jp snagata@ifrec.osaka-u.ac.jp.
Takaharu SakuragiLaboratory of Biochemistry & Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
Hiroyuki NojiDepartment of Applied Chemistry, The University of Tokyo, Tokyo 113-8656, Japan; wrikiya@nojilab.t.u-tokyo.ac.jp hnoji@appchem.t.u-tokyo.ac.jp snagata@ifrec.osaka-u.ac.jp.
Shigekazu NagataLaboratory of Biochemistry & Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan wrikiya@nojilab.t.u-tokyo.ac.jp hnoji@appchem.t.u-tokyo.ac.jp snagata@ifrec.osaka-u.ac.jp.
Osaka University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transmembrane protein 16F (TMEM16F) is a Ca

Indexed as

AnimalsAnoctaminsCell LineKineticsMembranes, ArtificialMicePhospholipidsPhospholipid Transfer ProteinsProtein Array AnalysisANO6 protein, mouseAnoctaminsMembranes, ArtificialPhospholipidsPhospholipid Transfer Proteinsmembrane proteinmicrosystemphospholipid scramblingsingle-molecule analysisTMEM16F

Identifiers

PMID29507235
PMCPMC5866571
OpenAlexW2792741936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.