Evidence map›Paper›PMID 29507184›Full record

ArticleMolecular and cellular biology2018

Developmental Decline in the MicroRNA 199a (miR-199a)/miR-214 Cluster in Human Fetal Lung Promotes Type II Cell Differentiation by Upregulating Key Transcription Factors.

Ritu Mishra, Houda Benlhabib, Wei Guo, Connie B Lerma Cervantes, Carole R Mendelson

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of NRF2 in immune modulator expression in developing lung.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  5. Review
  6. Review
  7. Higher PGDScientific reports · 2021
    Article
  8. Article
  9. MicroRNA and ROS Crosstalk in Cardiac and Pulmonary Diseases.International journal of molecular sciences · 2020
    Review
  10. Article
  11. Review
  12. Human lung development: recent progress and new challenges.Development (Cambridge, England) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ritu Mishra *Department of Biochemistry and North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Houda Benlhabib *Department of Biochemistry and North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Wei Guo *Department of Biochemistry and North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Connie B Lerma CervantesDepartment of Biochemistry and North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Carole R MendelsonDepartment of Biochemistry and North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA carole.mendelson@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USMarch of Dimes · US

Funding

Mechanisms in the Regulation of SP-A Gene Expression - Renewal - 1 - ResubmissionR01HL050022 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MAHENDROO, MALA S. · 1993 to 2022
$6.6M
NHLBI NIH HHS R01 HL050022
6 · The paper itself

Abstract

The major surfactant protein, SP-A (a product of the

Indexed as

Cell DifferentiationCyclic AMPDNA-Binding ProteinsDown-RegulationHumansMicroRNAsNF-kappa BTranscriptional ActivationTranscription FactorsUp-RegulationCyclic AMPDNA-Binding ProteinsMicroRNAsmirn199 microRNA, humanMIRN214 microRNA, humanNF-kappa BTranscription FactorsTTF1 protein, humanCOX-2CREBcyclic AMPfetal lungmiR-199aNF-κB

Identifiers

PMID29507184
PMCPMC5954188
OpenAlexW2790878306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.