Evidence map›Paper›PMID 29507073›Full record

ArticleAntimicrobial agents and chemotherapy2018

Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles.

Katrien Van Bocxlaer, Eric Gaukel, Deirdre Hauser, Seong Hee Park, Sara Schock, Vanessa Yardley, Ryan Randolph, Jacob J Plattner, Tejal Merchant, Simon L Croft and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Efficacy of oleylphosphocholine in experimental cutaneous leishmaniasis.The Journal of antimicrobial chemotherapy · 2023
    Article
  3. Effect of topical berberine in murine cutaneous leishmaniasis lesions.The Journal of antimicrobial chemotherapy · 2022
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
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  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Katrien Van BocxlaerLondon School of Hygiene & Tropical Medicine, Faculty of Infections and Tropical Diseases, London, United Kingdom.
Eric GaukelScynexis Inc., Research Triangle Park, North Carolina, USA.
Deirdre HauserScynexis Inc., Research Triangle Park, North Carolina, USA.
Seong Hee ParkScynexis Inc., Research Triangle Park, North Carolina, USA.
Sara SchockScynexis Inc., Research Triangle Park, North Carolina, USA.
Vanessa YardleyLondon School of Hygiene & Tropical Medicine, Faculty of Infections and Tropical Diseases, London, United Kingdom.
Ryan RandolphScynexis Inc., Research Triangle Park, North Carolina, USA.
Jacob J PlattnerAnacor Pharmaceuticals, Inc., Palo Alto, California, USA.
Tejal MerchantAnacor Pharmaceuticals, Inc., Palo Alto, California, USA.
Simon L CroftLondon School of Hygiene & Tropical Medicine, Faculty of Infections and Tropical Diseases, London, United Kingdom simon.croft@lshtm.ac.uk.
Robert T JacobsAnacor Pharmaceuticals, Inc., Palo Alto, California, USA.
Stephen A WringScynexis Inc., Research Triangle Park, North Carolina, USA.
Triangle · USLondon School of Hygiene & Tropical Medicine · GBScynexis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous leishmaniasis (CL) is caused by several species of the protozoan parasite

Indexed as

Administration, OralAdministration, TopicalAntiprotozoal AgentsBoron CompoundsLeishmaniasis, CutaneousAntiprotozoal AgentsBoron Compoundsbenzoxaborolescutaneous leishmaniasisLeishmaniapharmacokineticstopical

Identifiers

PMID29507073
PMCPMC5923108
OpenAlexW2790526432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.