Evidence map›Paper›PMID 29507057›Full record

ArticleG3 (Bethesda, Md.)2018

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of

James L Lissemore, Elyse Connors, Ying Liu, Li Qiao, Bing Yang, Mark L Edgley, Stephane Flibotte, Jon Taylor, Vinci Au, Donald G Moerman and 1 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. ThemicroPublication biology · 2026
    Article
  2. Organismal Roles of Hsp90.Biomolecules · 2023
    Review
  3. Review
  4. microPublication biology · 2022
    Article
  5. Article
  6. Biology of theGenetics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

James L LissemoreBiology Department, John Carroll University, University Heights, OH 44118 jlissemore@jcu.edu.ORCID 0000-0002-1418-2285
Elyse ConnorsDepartment of Biology, Syracuse University, NY 13244.
Ying LiuDepartment of Biology, Syracuse University, NY 13244.
Li QiaoDepartment of Biology, Syracuse University, NY 13244.
Bing YangDepartment of Biology, Syracuse University, NY 13244.
Mark L EdgleyDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.ORCID 0000-0001-9113-8862
Stephane FlibotteDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
Jon TaylorDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
Vinci AuDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
Donald G MoermanDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
Eleanor M MaineDepartment of Biology, Syracuse University, NY 13244.
Syracuse University · USUniversity of British Columbia · CAJohn Carroll University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

In a genetic screen to identify genes that promote GLP-1/Notch signaling in

Indexed as

Signal TransductionAllelesAmino Acid SequenceAnimalsBase SequenceCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA-Binding ProteinsGerm CellsHSP90 Heat-Shock ProteinsLoss of Function MutationMolecular ChaperonesPhenotypePhysical Chromosome MappingReceptors, NotchCaenorhabditis elegans ProteinsDAF-21 protein, C elegansDNA-Binding ProteinsGlp-1 protein, C elegansHSP90 Heat-Shock ProteinsLAG-1 protein, C elegansMolecular ChaperonesReceptors, NotchC. elegansgermline stem cellsGLP-1HSP90Notch

Identifiers

PMID29507057
PMCPMC5940146
OpenAlexW2793430158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.