Evidence map›Paper›PMID 29506481›Full record

Observational studyBMC geriatrics2018

Does sarcopenia predict change in mobility after hip fracture? a multicenter observational study with one-year follow-up.

Ole Martin Steihaug, Clara Gram Gjesdal, Bård Bogen, Målfrid Holen Kristoffersen, Gunhild Lien, Karl Ove Hufthammer, Anette Hylen Ranhoff

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04075461 (Is arthroplaSty bEtter Than interNal Fixation in the undiSplaced Femoral nEck Fracture? A National Pragmatical Randomized Controlled Trial - the SENSE Trial), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04075461 nacompletednot on this mapstarted 2020, after this paper: background citation

Is arthroplaSty bEtter Than interNal Fixation in the undiSplaced Femoral nEck Fracture? A National Pragmatical Randomized Controlled Trial - the SENSE Trial

TypeinterventionalSponsorUniversity of Southern DenmarkRan2020 to 2025Enrolled330ConditionsUndisplaced Fracture, Femoral Neck Fractures, Internal Fixation, ComplicationsArmsArthroplasty, Internal fixation
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Late-life disability following the action for health in diabetes (Look AHEAD) trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Trial
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  5. Review
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  9. Definitions and adverse outcomes of sarcopenia in older patients in orthopedic and trauma care: A scoping review on current evidence.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  10. Frailty Status, Sedentary Behaviors, and Risk of Incident Bone Fractures.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ole Martin SteihaugKavli Research Centre for Geriatrics and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway.ORCID 0000-0002-1849-3910
Clara Gram GjesdalDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Bård BogenKavli Research Centre for Geriatrics and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway.
Målfrid Holen KristoffersenDepartment of Orthopedics, Haukeland University Hospital, Bergen, Norway.
Gunhild LienDepartment of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.
Karl Ove HufthammerCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway.
Anette Hylen RanhoffKavli Research Centre for Geriatrics and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway. ahranhoff@yahoo.no.

Funding

Helse Vest 911829
6 · The paper itself

Abstract

backgroundPatients with hip fracture frequently have sarcopenia and are at great risk of loss of mobility. We have investigated if sarcopenia predicts change in mobility after hip fracture.

methodsThis is a prospective, multicenter observational study with one-year follow-up. Patients with hip fracture who were community-living and capable of walking before the fracture were included at three hospitals in Norway (2011-2013). The primary outcome of the study was change in mobility, measured by the New Mobility Score (NMS). Sarcopenia was determined postoperatively by anthropometry, grip strength, and NMS.

resultsWe included 282 participants and sarcopenia status was determined in 201, of whom 38% (77/201) had sarcopenia, 66% (128/194) had low muscle mass, 52% (116/222) had low grip strength and 8% (20/244) had low pre-fracture mobility (NMS < 5). Sarcopenia did not predict change in mobility (effect 0.2 points; 95% CI -0.5 to 0.9, P = 0.6), but it was associated with having lower mobility at one-year (NMS 5.8 (SD 2.3) vs. 6.8 (SD 2.2), P = 0.003), becoming a resident of a nursing home (odds ratio 3.2, 95% CI 0.9 to 12.4, P = 0.048), and the combined endpoint of becoming a resident of a skilled nursing home or death (odds ratio 3.6, 95% CI 1.2 to 12.2, P = 0.02).

conclusionsSarcopenia did not predict change in mobility in the year after hip fracture.

Indexed as

Mobility LimitationAgedAged, 80 and overFemaleFollow-Up StudiesHip FracturesHumansMaleNorwayPredictive Value of TestsProspective StudiesSarcopeniaTime FactorsWalkingActivities of daily livingHip fracturesIndependent livingMobility limitationSarcopeniaSkilled nursing facilities

Identifiers

PMID29506481
PMCPMC5836393

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.