Evidence map›Paper›PMID 29505319›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2018

Mild Traumatic Brain Injury and Aggression, Impulsivity, and History of Other- and Self-Directed Aggression.

Caterina Mosti, Emil F Coccaro

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Personality disorder and mild traumatic brain injury.Personality and mental health · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. The Relationship between Sport-Related Concussion and Sensation-Seeking.International journal of molecular sciences · 2020
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caterina MostiFrom the Clinical Neuroscience Research Unit, Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, University of Chicago (CM, EFC).
Emil F CoccaroFrom the Clinical Neuroscience Research Unit, Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, University of Chicago (CM, EFC).
University of Chicago · US

Funding

Fluoxetine and Divalproex:Treatment Correlates in Intermittent Explosive DisorderR01MH066984 · NIMH · UNIVERSITY OF CHICAGO · PI COCCARO, EMIL FRANK · 2003 to 2007
$3.3M
Intermittent Explosive Disorder: A Family StudyR01MH060836 · NIMH · UNIVERSITY OF CHICAGO · PI COCCA, EMIL FRANK · 2001 to 2005
$2.8M
Neuroinflammation and AggressionR01MH104673 · NIMH · UNIVERSITY OF CHICAGO · PI COCCARO, EMIL FRANK · 2015 to 2018
$2.5M
NIMH NIH HHS R01 MH060836NIMH NIH HHS R01 MH066984NIMH NIH HHS R01 MH104673
6 · The paper itself

Abstract

Mild traumatic brain injury (mTBI) is highly prevalent, with an estimated occurrence in the United States of more than 1.3 million per year. While one consequence of mTBI is impulsive aggressive behavior, very few studies have examined the relationship between history of mTBI and aggressive behavior in impulsively aggressive individuals. The authors examined the relationship between history of mTBI in a healthy control group (HC; N=453), a control group with psychiatric disorders (PC; N=486), and individuals with intermittent explosive disorder (IED; N=695), a disorder of primary impulsive aggression. Results demonstrated that IED study participants were significantly more likely to have a history of mTBI (with or without history of a brief loss of consciousness [LOC]) compared with both HC and PC participants. A similar observation was made with regard to self-directed aggression (i.e., suicidal or self-injurious behavior), although group differences were only among those with mTBI with LOC. For both other- and self-directed aggression variables, the authors observed a stepwise increase in dimensional aggression and impulsivity scores across participants as a function of mTBI history. Given that impulsive aggressive behavior begins very early in life, these data are consistent with the hypothesis that lifelong presence of an impulsive aggressive temperament places impulsive aggressive individuals in circumstances that put them at greater risk for mTBI compared with other individuals with and without nonimpulsive aggressive psychopathology.

Indexed as

AggressionImpulsive BehaviorSelf-Injurious BehaviorAdultBrain ConcussionDisruptive, Impulse Control, and Conduct DisordersFemaleHumansMaleTraumatic Brain InjuryViolence/Aggression

Identifiers

PMID29505319
PMCPMC6081254
OpenAlexW2792020053

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.