Evidence map›Paper›PMID 29505186›Full record

ArticleThe Journal of clinical psychiatry

Effects of Rapastinel (Formerly GLYX-13) on Serum Brain-Derived Neurotrophic Factor in Obsessive-Compulsive Disorder.

Omer Linkovski, Hanyang Shen, Jordana Zwerling, Maria Filippou-Frye, Booil Jo, Elisabeth Cordell, Thomas B Cooper, Helen Blair Simpson, Ronald M Burch, Joseph R Moskal and 2 more

Open access · greenAbstract readControlled Clinical TrialLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of clinical psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Omer LinkovskiDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Hanyang ShenDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Jordana ZwerlingDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Maria Filippou-FryeDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Booil JoDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Elisabeth CordellDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Thomas B CooperAnalytical Psychopharmacology Laboratory, Nathan Kline Institute, Research Foundation for Mental Hygiene of New York State, Orangeburg, New York, USA.
Helen Blair SimpsonDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Ronald M BurchAptinyx, Inc, Evanston, Illinois, USA.
Joseph R MoskalAptinyx, Inc, Evanston, Illinois, USA.
Francis LeeDepartment of Psychiatry, Weill Cornell Medical College, New York, New York, USA.
Carolyn I Rodriguezcarolynrodriguez@stanford.edu.
Stanford University · USCornell University · USNew York State Psychiatric InstituteVA Palo Alto Health Care System · US

Funding

NMDAR Modulation As A Therapeutic Target and Probe of Neural Dysfunction in OCDR01MH105461 · NIMH · STANFORD UNIVERSITY · PI RODRIGUEZ, CAROLYN I · 2015 to 2020
$4.2M
Novel Interventions for Adults with Obsessive-Compulsive DisorderK23MH092434 · NIMH · STANFORD UNIVERSITY · PI RODRIGUEZ, CAROLYN I · 2011 to 2015
$805k
Enhancing Patient-Oriented Research and Training in OCDK24MH091555 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SIMPSON, HELEN BLAIR · 2010 to 2014
$742k
NIMH NIH HHS K23 MH092434NIMH NIH HHS K24 MH091555NIMH NIH HHS R01 MH105461
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultBrain-Derived Neurotrophic FactorExcitatory Amino Acid AntagonistsHumansInfusions, IntravenousKetamineMiddle AgedObsessive-Compulsive DisorderOligopeptidesYoung AdultBrain-Derived Neurotrophic FactorExcitatory Amino Acid AntagonistsGLYX-13 peptideKetamineOligopeptides

Identifiers

PMID29505186
PMCPMC7370843
OpenAlexW2794084139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.