Evidence map›Paper›PMID 29504936›Full record

ArticleeLife2018

Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance.

Dorine Jeanne Mariëtte du Mee, Maxim Ivanov, Joseph Paul Parker, Stephen Buratowski, Sebastian Marquardt

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dorine Jeanne Mariëtte du MeeDepartment of Plant and Environmental Sciences, Copenhagen Plant Science Centre, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0002-0037-7882
Maxim IvanovDepartment of Plant and Environmental Sciences, Copenhagen Plant Science Centre, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0001-7548-3316
Joseph Paul ParkerDepartment of Plant and Environmental Sciences, Copenhagen Plant Science Centre, University of Copenhagen, Frederiksberg, Denmark.
Stephen BuratowskiDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States.ORCID 0000-0003-0440-3926
Sebastian MarquardtDepartment of Plant and Environmental Sciences, Copenhagen Plant Science Centre, University of Copenhagen, Frederiksberg, Denmark.ORCID 0000-0003-1709-2717
University of Copenhagen · DKHarvard University · US

Funding

The RNA Polymerase II Transcription CycleR01GM056663 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Stephen Buratowski · 1999 to 2026
$11.7M
NIGMS NIH HHS GM56663NIGMS NIH HHS R01 GM056663
6 · The paper itself

Abstract

Most DNA in the genomes of higher organisms does not code for proteins. RNA Polymerase II (Pol II) transcribes non-coding DNA into long non-coding RNAs (lncRNAs), but biological roles of lncRNA are unclear. We find that mutations in the yeast lncRNA

Indexed as

Genome, MitochondrialGenomic InstabilityTranscription, GeneticGene Expression Regulation, FungalMitochondriaMitochondrial Proton-Translocating ATPasesRNA, Long NoncodingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsATP17 protein, S cerevisiaeMitochondrial Proton-Translocating ATPasesRNA, Long NoncodingSaccharomyces cerevisiae ProteinsChromatinchromosomesevolutionary biologygenesGenome StabilitygenomicslncRNAPervasive transcriptionRNA Polymerase IIS. cerevisiaeTranscriptional Interference

Identifiers

PMID29504936
PMCPMC5837560
OpenAlexW2791548497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.