Evidence map›Paper›PMID 29504292›Full record

ReviewJournal of clinical neurology (Seoul, Korea)2018

Current Clinical Applications of Diffusion-Tensor Imaging in Neurological Disorders.

Woo Suk Tae, Byung Joo Ham, Sung Bom Pyun, Shin Hyuk Kang, Byung Jo Kim

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical neurology (Seoul, Korea), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06857136 (The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH), which is not on this map. Cited by 164 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06857136 completednot on this mapstarted 2021, after this paper: background citation

The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH

TypeobservationalSponsorFondazione I.R.C.C.S. Istituto Neurologico Carlo BestaRan2021 to 2024Enrolled29ConditionsHydrocephalus, Normal Pressure Hydrocephalus
3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  8. Predicting glioblastoma progression using MR diffusion tensor imaging: A systematic review.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Pooled it
  9. Transcranial Pulse Stimulation Enhances Dexterity in Parkinson's Disease: A Randomized Sham-Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2026
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104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Woo Suk TaeBrain Convergence Research Center, Korea University, Seoul, Korea.
Byung Joo HamBrain Convergence Research Center, Korea University, Seoul, Korea.
Sung Bom PyunBrain Convergence Research Center, Korea University, Seoul, Korea.
Shin Hyuk KangBrain Convergence Research Center, Korea University, Seoul, Korea.
Byung Jo KimBrain Convergence Research Center, Korea University, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the structure of white matter. The signal contrast in DTI is generated by differences in the Brownian motion of the water molecules in brain tissue. Postprocessed DTI scalars can be used to evaluate changes in the brain tissue caused by disease, disease progression, and treatment responses, which has led to an enormous amount of interest in DTI in clinical research. This review article provides insights into DTI scalars and the biological background of DTI as a relatively new neuroimaging modality. Further, it summarizes the clinical role of DTI in various disease processes such as amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's dementia, epilepsy, ischemic stroke, stroke with motor or language impairment, traumatic brain injury, spinal cord injury, and depression. Valuable DTI postprocessing tools for clinical research are also introduced.

Indexed as

diffusion-tensor imagingdiffusion-tensor imaging scalarneurological disorderspostprocessing

Identifiers

PMID29504292
PMCPMC5897194

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.