ArticlePhysiological reports2018
The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia.
Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Vitamin D Status and Oxidative Stress in Children with Sickle Cell Anaemia in Sagamu, Nigeria.Sultan Qaboos University medical journal · 2025Article
- Theoretical exploration about the thermal stability and detonation properties of nitro-substituted hypoxanthine.Journal of molecular modeling · 2020Article
- The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia.Physiological reports · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Red cells from patients with sickle cell anemia (SCA) are under greater oxidative challenge than those from normal individuals. We postulated that oxidants generated by xanthine oxidase (XO) and hypoxanthine (HO) contribute to the pathogenesis of SCA through altering solute permeability. Sickling, activities of the main red cell dehydration pathways (P
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Registered trials
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