Evidence map›Paper›PMID 29504262›Full record

ArticleObesity (Silver Spring, Md.)2018

High Fat and Sugar Consumption During Ad Libitum Intake Predicts Weight Gain.

Emma J Stinson, Paolo Piaggi, Mostafa Ibrahim, Colleen Venti, Jonathan Krakoff, Susanne B Votruba

Open access · hybridAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Review
  3. The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Precision Nutrition: Recent Advances in Obesity.Physiology (Bethesda, Md.) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emma J StinsonPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.ORCID 0000-0003-4875-7048
Paolo PiaggiPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.ORCID 0000-0003-2774-9161
Mostafa IbrahimPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.
Colleen VentiPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.
Jonathan KrakoffPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.
Susanne B VotrubaPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, Phoenix, Arizona, USA.
Arizona Research Center · US

Funding

Regulators of Food IntakeZIADK069091 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KRAKOFF, JONATHAN · 2009 to 2025
$15.0M
Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

objectiveTo determine how macronutrients accompanying foods with high energy density (EnDen) affect energy intake and weight gain.

methodsA total of 214 subjects (130 males, BMI: 32 ± 7 kg/m

resultsEnDen was associated with BMI (r = 0.28, P < 0.0001), percent body fat (r = 0.18, P = 0.007), and percent intake from HF/HP (r = 0.34, P < 0.0001), HF/HSS (r = 0.31, P < 0.0001), LF/HP (r = -0.37, P < 0.0001) and LF/HSS (r = -0.68, P < 0.0001). The %WMEN was associated with EnDen (r = 0.16, P = 0.01), HF/HSS (r = 0.33, P < 0.0001), and LF/HP intake (r = -0.25, P = 0.0002). In a multivariate model, only HF/HSS intake remained a significant predictor of %WMEN (β = 1.4% per 1% change, P < 0.0001). The percent intake from HF/HSS (r = 0.23, P = 0.02), not EnDen (P = 0.54), was associated with weight gain, even after adjusting for follow-up time (in years) and covariates.

conclusionsRelatively greater consumption of HF/HSS foods independently predicted overeating and weight gain. Nutrient compositions of high-EnDen foods may be important for weight management.

Indexed as

AdolescentAdultAgedBody WeightDietary FatsEatingFemaleHumansMaleMiddle AgedSugarsWeight GainYoung AdultDietary FatsSugars

Identifiers

PMID29504262
PMCPMC5866204
OpenAlexW2792305137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.