Evidence map›Paper›PMID 29504181›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Comparison of

Neil J Stewart, Ho-Fung Chan, Paul J C Hughes, Felix C Horn, Graham Norquay, Madhwesha Rao, Denise P Yates, Rob H Ireland, Matthew Q Hatton, Bilal A Tahir and 6 more

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Deep Learning Reconstruction forMagnetic resonance in medicine · 2026
    Article
  5. Article
  6. Article
  7. Magnetic resonance in medicine · 2025
    Article
  8. DynamicJHLT open · 2025
    Article
  9. Article
  10. UltrasensitiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  11. Article
  12. HyperpolarizedAcademic radiology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Image Phenotyping of Preterm-Born Children Using HyperpolarizedAmerican journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Neil J StewartAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Ho-Fung ChanAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Paul J C HughesAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Felix C HornAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Graham NorquayAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Madhwesha RaoAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Denise P YatesNovartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Rob H IrelandAcademic Unit of Clinical Oncology, University of Sheffield, Sheffield, UK.
Matthew Q HattonAcademic Unit of Clinical Oncology, University of Sheffield, Sheffield, UK.
Bilal A TahirAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Paul FordAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Andrew J SwiftAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Rod LawsonSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Helen MarshallAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Guilhem J CollierAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Jim M WildAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.

Funding

British Heart Foundation SP/14/6/31350Department of Health NIHR-RP-R3-12-027Medical Research Council MR/M008894/1Wellcome Trust 205188/Z/16/Z
6 · The paper itself

Abstract

backgroundTo support translational lung MRI research with hyperpolarized PURPOSE/HYPOTHESIS: To compare hyperpolarized STUDY TYPE: Retrospective. POPULATION: Fourteen healthy nonsmokers (HN), five exsmokers (ES), five patients with chronic obstructive pulmonary disease (COPD), and 16 patients with nonsmall-cell lung cancer (NSCLC). FIELD STRENGTH/SEQUENCE: 1.5T. NSCLC, COPD patients and selected HN subjects underwent 3D balanced steady-state free-precession lung ventilation MRI using both ASSESSMENT: Ventilated volume percentages (VV%) and mean apparent diffusion coefficients (ADC) were derived from imaging. COPD patients performed the whole MR protocol in four separate scan sessions to assess repeatability. Same-day pulmonary function tests were performed. STATISTICAL TESTS: Intermetric correlations: Spearman's coefficient. Intergroup/internuclei differences: analysis of variance / Wilcoxon's signed rank. Repeatability: coefficient of variation (CV), intraclass correlation (ICC) coefficient.

resultsA significant positive correlation between LEVEL OF EVIDENCE: 3 Technical Efficacy Stage 2 J. Magn. Reson. Imaging 2018.

Indexed as

chronic obstructive pulmonary diseasehelium-3hyperpolarized gaslung cancerlung MRIrepeatabilityxenon-129

Identifiers

PMID29504181
PMCPMC6175321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.