Evidence map›Paper›PMID 29504143›Full record

ReviewJournal of medical primatology2018

A case report of ovotesticular disorder of sex development (OT-DSD) in a baboon (Papio spp.) and a brief review of the non-human primate literature.

Ekaterina Perminov, Sara Mangosing, Alexandra Confer, Olga Gonzalez, Jason R Crawford, Natalia Schlabritz-Loutsevitch, Shyamesh Kumar, Edward Dick

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical primatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ekaterina PerminovSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Sara MangosingSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Alexandra ConferSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Olga GonzalezSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Jason R CrawfordVeterinary Pathology Services, Joint Pathology Center, Silver Spring, MD, USA.
Natalia Schlabritz-LoutsevitchTexas Tech University Health Sciences Center at the Permian Basin, Odessa, TX, USA.
Shyamesh KumarSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.ORCID 0000-0001-9261-2263
Edward DickSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
WNV REPLIVAX VACCINE IN NON-HUMAN PRIMATESP51RR013986 · NCRR · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI DAVIS, MICHAEL DUFF · 1999 to 2011
$79.1M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR016228 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.9M
NCRR NIH HHS C06 RR016228NCRR NIH HHS P51 RR013986NIH HHS P51 OD011133
6 · The paper itself

Abstract

Disorders of sexual development are rare in non-human primates. We report a case of true hermaphroditism in a 19-year-old, nulliparous, female baboon (Papio spp.). At necropsy, the animal was obese with adequate muscle mass and hydration. Reproductive organs appeared normal with the exception of 2 firm nodular structures in the myometrium (1-1.5 cm diameter) and a thickened, dark endocervical mucosa. Histologically, both gonads were ovotestes and contained discrete areas of ovarian and testicular tissue. There were follicles in various stages of development surrounded by ovarian stroma. Other areas contained hypoplastic seminiferous tubules lined by Sertoli cells, but lacked germ cells and spermatozoa. The uterine lesions were consistent with adenomyosis and cystic endometrial hyperplasia. Cervical lesions were consistent with atypical glandular hyperplasia and squamous metaplasia with dysplasia. We report the first case of ovotesticular disorder of sexual development (OT-DSD), or true hermaphroditism in a baboon.

Indexed as

PapioAnimalsFemaleMonkey DiseasesOvotesticular Disorders of Sex DevelopmentAdenomyosisOvotestesTrue hermaphrodite

Identifiers

PMID29504143
PMCPMC5934321

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.