Evidence map›Paper›PMID 29503975›Full record

ArticleACS omega2018

Manipulation of the Geometry and Modulation of the Optical Response of Surfactant-Free Gold Nanostars: A Systematic Bottom-Up Synthesis.

Agampodi S De Silva Indrasekara, Sean F Johnson, Ren A Odion, Tuan Vo-Dinh

Abstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Agampodi S De Silva IndrasekaraDepartment of Biomedical Engineering, Fitzpatrick Institute of Photonics, and Department of Chemistry, Duke University, Durham, North Carolina 27708, United States.
Sean F JohnsonDepartment of Biomedical Engineering, Fitzpatrick Institute of Photonics, and Department of Chemistry, Duke University, Durham, North Carolina 27708, United States.
Ren A OdionDepartment of Biomedical Engineering, Fitzpatrick Institute of Photonics, and Department of Chemistry, Duke University, Durham, North Carolina 27708, United States.
Tuan Vo-DinhDepartment of Biomedical Engineering, Fitzpatrick Institute of Photonics, and Department of Chemistry, Duke University, Durham, North Carolina 27708, United States.

Funding

Nanoplasmonics-based molecular analysis tool for molecular biomarkers of cancerR21CA196426 · NCI · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2015 to 2017
$676k
Bloodborne tropical pathogen detection using multiple nanophotonic arraysR21AI120981 · NIAID · DUKE UNIVERSITY · PI TAYLOR, STEVE MYER, VO-DINH, TUAN · 2016 to 2017
$407k
NCI NIH HHS R21 CA196426NIAID NIH HHS R21 AI120981
6 · The paper itself

Abstract

Among plasmonic nanoparticles, surfactant-free branched gold nanoparticles have exhibited exceptional properties as a nanoplatform for a wide variety of applications ranging from surface-enhanced Raman scattering sensing and imaging applications to photothermal treatment and photoimmunotherapy for cancer treatments. The effectiveness and reliability of branched gold nanoparticles in biomedical applications strongly rely on the consistency and reproducibility of physical, chemical, optical, and therapeutic properties of nanoparticles, which are mainly governed by their morphological features. Herein, we present an optimized bottom-up synthesis that improves the reproducibility and homogeneity of the gold-branched nanoparticles with desired morphological features and optical properties. We identified that the order of reagent addition is crucial for improved homogeneity of the branched nature of nanoparticles that enable a high batch-to-batch reproducibility and reliability. In addition, a different combination of the synthesis parameters, in particular, additive halides and concentration ratios of reactive Au to Ag and Au to Au seeds, which yield branched nanoparticle of similar localized surface plasmon resonances but with distinguishable changes in the dimensions of the branches, was realized. Overall, our study introduces the design parameters for the purpose-tailored manufacturing of surfactant-free gold nanostars in a reliable manner.

Identifiers

PMID29503975
PMCPMC5830692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.