Evidence map›Paper›PMID 29503973›Full record

ArticleACS omega2018

Novel FR-900493 Analogues That Inhibit the Outgrowth of

Katsuhiko Mitachi, Hyun Gi Yun, Sara M Kurosu, Shakiba Eslamimehr, Maddie R Lemieux, Lada Klaić, William M Clemons, Michio Kurosu

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. DPAGT1-Perspective as an Anticancer Drug Target.Molecules (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor.Angewandte Chemie (International ed. in English) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Structure-based drug discovery by targetingFuture medicinal chemistry · 2019
    Article
  17. Article
  18. Article
  19. Article
  20. Inhibition ofJournal of molecular pharmaceutics & organic process research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Katsuhiko MitachiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.
Hyun Gi YunDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, Pasadena, California 91125, United States.
Sara M KurosuDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.
Shakiba EslamimehrDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.
Maddie R LemieuxDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.
Lada KlaićDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, Pasadena, California 91125, United States.
William M ClemonsDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd, Pasadena, California 91125, United States.
Michio KurosuDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.
University of Tennessee Health Science Center · USCalifornia Institute of Technology · US

Funding

Mechanistic details of key integral-membrane enzymes for antimicrobial discoveryR01GM114611 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI William M. Clemons, Michio Kurosu · 2016 to 2026
$4.2M
Expansion of spectrum of activity of pleuromutilin for MDR Gram-negative bacteriaR21AI119796 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KUROSU, MICHIO · 2015 to 2016
$431k
NIAID NIH HHS R21 AI119796NIGMS NIH HHS R01 GM114611
6 · The paper itself

Abstract

The spectrum of antibacterial activity for the nucleoside antibiotic FR-900493 (

Identifiers

PMID29503973
PMCPMC5830699
OpenAlexW2792059098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.