Evidence map›Paper›PMID 29503970›Full record

ArticleACS omega2018

Aptamer-Based Impedimetric Assay of Arsenite in Water: Interfacial Properties and Performance.

Karlene Vega-Figueroa, Jaime Santillán, Valerie Ortiz-Gómez, Edwin O Ortiz-Quiles, Beatriz A Quiñones-Colón, David A Castilla-Casadiego, Jorge Almodóvar, Marvin J Bayro, José A Rodríguez-Martínez, Eduardo Nicolau

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Advances in Electrochemical Detection Electrodes for As(III).Nanomaterials (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Karlene Vega-FigueroaDepartment of Biology and Department of Physics, University of Puerto Rico, Rio Piedras Campus, P.O. Box 23346, San Juan, Puerto Rico 00931-3346, United States.
Jaime SantillánDepartment of Biology and Department of Physics, University of Puerto Rico, Rio Piedras Campus, P.O. Box 23346, San Juan, Puerto Rico 00931-3346, United States.
Valerie Ortiz-GómezDepartment of Biology and Department of Physics, University of Puerto Rico, Rio Piedras Campus, P.O. Box 23346, San Juan, Puerto Rico 00931-3346, United States.
Edwin O Ortiz-QuilesDepartment of Chemistry, University of Puerto Rico, Rio Piedras Campus, 17 Ave. Universidad Ste. 1701, San Juan, Puerto Rico 00925-2537, United States.
Beatriz A Quiñones-ColónDepartment of Chemical Engineering, University of Puerto Rico Mayaguez, Call Box 9000, Mayaguez, Puerto Rico 00681-9000, United States.
David A Castilla-CasadiegoDepartment of Chemical Engineering, University of Puerto Rico Mayaguez, Call Box 9000, Mayaguez, Puerto Rico 00681-9000, United States.
Jorge AlmodóvarDepartment of Chemical Engineering, University of Puerto Rico Mayaguez, Call Box 9000, Mayaguez, Puerto Rico 00681-9000, United States.
Marvin J BayroDepartment of Chemistry, University of Puerto Rico, Rio Piedras Campus, 17 Ave. Universidad Ste. 1701, San Juan, Puerto Rico 00925-2537, United States.
José A Rodríguez-MartínezDepartment of Biology and Department of Physics, University of Puerto Rico, Rio Piedras Campus, P.O. Box 23346, San Juan, Puerto Rico 00931-3346, United States.
Eduardo NicolauDepartment of Chemistry, University of Puerto Rico, Rio Piedras Campus, 17 Ave. Universidad Ste. 1701, San Juan, Puerto Rico 00925-2537, United States.
University of Puerto Rico System · PRUniversity of Puerto Rico at Río Piedras · PRUniversity of Puerto Rico-Mayaguez · PR

Funding

Upgrade Laboratories Facilities at UPR-Rio PiedrasR25GM061151 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI CARBALLEIRA, NESTOR MANUEL · 2001 to 2023
$32.5M
NIGMS NIH HHS R25 GM061151
6 · The paper itself

Abstract

In this work, we explore the use of electrochemical methods (i.e., impedance) along with the arsenic-specific aptamer (ArsSApt) to fabricate and study the interfacial properties of an arsenic (As(III)) sensor. The ArsSApt layer was self-assembled on a gold substrate, and upon binding of As(III), a detectable change in the impedimetric signal was recorded because of conformational changes at the interfacial layer. These interfacial changes are linearly correlated with the concentration of arsenic present in the system. This target-induced signal was utilized for the selective detection of As(III) with a linear dynamic range of 0.05-10 ppm and minimum detectable concentrations of ca. 0.8 μM. The proposed system proved to be successful mainly because of the combination of a highly sensitive electrochemical platform and the recognized specificity of the ArsSApt toward its target molecule. Also, the interaction between the ArsSApt and the target molecule (i.e., arsenic) was explored in depth. The obtained results in this work are aimed at proving the development of a simple and environmentally benign sensor for the detection of As(III) as well as in elucidating the possible interactions between the ArsSApt and arsenic molecules.

Identifiers

PMID29503970
PMCPMC5830693
OpenAlexW2789476388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.