Evidence map›Paper›PMID 29503856›Full record

ArticleEJNMMI radiopharmacy and chemistry2017

Generation of fluorescently labeled tracers - which features influence the translational potential?

Fijs W B van Leeuwen, Bart Cornelissen, Federico Caobelli, Laura Evangelista, Latifa Rbah-Vidal, Silvana Del Vecchio, Catarina Xavier, Jacques Barbet, Marion de Jong

Abstract read
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Targeted optical fluorescence imaging: a meta-narrative review and future perspectives.European journal of nuclear medicine and molecular imaging · 2021
    Review
  7. Article
  8. Necrosis binding of Ac-LysEJNMMI research · 2021
    Article
  9. Contrast media & molecular imaging · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fijs W B van Leeuwen1Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Bart Cornelissen2Department of Oncology, CRUK&MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK.
Federico Caobelli3Department of Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Laura Evangelista4Nuclear Medicine and Molecular Imaging Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Latifa Rbah-Vidal5CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Silvana Del Vecchio6Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
Catarina Xavier7In vivo Cellular and Molecular Imaging Lab (ICMI)-Department, Vrije Universiteit Brussel, Ixelles, Belgium.
Jacques Barbet5CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Marion de Jong8Department of Radiology & Nuclear Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.

Funding

Cancer Research UK 16466Cancer Research UK 23970
6 · The paper itself

Abstract

Given the increasing exploration of fluorescent tracers in the field of nuclear medicine, a need has risen for practical development guidelines that can help improve the translation aspects of fluorescent tracers. This editorial discusses the does and don'ts in developing fluorescence tracers. It has been put forward by the European Association of Nuclear Medicine (EANM) Translational Molecular Imaging & Therapy committee and has been approved by the EANM board.

Indexed as

Dual-modalityFluorescenceImage guided surgeryMolecular imagingNuclear medicineTracers

Identifiers

PMID29503856
PMCPMC5824706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.