ArticleCurrent opinion in behavioral sciences2018
Current perspectives on incentive salience and applications to clinical disorders.
Article in Current opinion in behavioral sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task.Translational psychiatry · 2022Pooled it
- Amplification of positivity for depression and anxiety: Neural prediction of treatment response.Behaviour research and therapy · 2024Trial
- Amplification of Positivity Treatment for Anxiety and Depression: A Randomized Experimental Therapeutics Trial Targeting Social Reward Sensitivity to Enhance Social Connectedness.Biological psychiatry · 2024Trial
- The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Trial
- Cued unpredictable intermittent access exacerbates loss of control over ethanol drinking.Neuropharmacology · 2026Article
- Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias.Current research in neurobiology · 2026Article
- Cued unpredictable intermittent access exacerbates loss of control over ethanol drinking.bioRxiv : the preprint server for biology · 2026Article
- Probing the habitual and compulsive-like basis of (dys)functional checking in the Observing Response Task, a rodent analogue relevant to obsessive-compulsive disorder.Psychopharmacology · 2026Article
- Mesolimbic dopamine signaling mediates increased hedonic feeding and food seeking in lactating mice.bioRxiv : the preprint server for biology · 2026Article
- Inhaled N, N-dimethyltryptamine diminishes connectivity between the ventral tegmental area and the nucleus accumbens: relevance to pathologies of mesolimbic and mesocortical pathways.Scientific reports · 2025Article
- Extinction of outcome-specific Pavlovian-to-instrumental transfer (PIT), instrumental outcome devaluation, and reward-related attentional capture are predicted by affect-driven impulsivity.Learning & behavior · 2025Article
- Addictive-like behavioural traits in pet dogs with extreme motivation for toy play.Scientific reports · 2025Article
- Frontostriatal Networks Undergo Functional Specialization during Adolescence That Follows a Ventral-Dorsal Gradient: Developmental Trajectories and Longitudinal Associations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Food cravings are associated with increased self-regulation, even in the face of strong instigation habits: A longitudinal study of the transition to plant-based eating.Applied psychology. Health and well-being · 2025Article
- The Limbic System in Co-Occurring Substance Use and Anxiety Disorders: A Narrative Review Using the RDoC Framework.Brain sciences · 2024Review
- Dopamine, activation of ingestion and evaluation of response efficacy: a focus on the within-session time-course of licking burst number.Psychopharmacology · 2024Review
- Differential effects of acute and prolonged morphine withdrawal on motivational and goal-directed control over reward-seeking behaviour.Addiction biology · 2024Article
- Ventromedial frontoinsular connectivity is associated with long-term smoking behavior change in aging.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Solving the Global Opioid Crisis: Incorporating Genetic Addiction Risk Assessment with Personalized Dopaminergic Homeostatic Therapy and Awareness Integration Therapy.Journal of addiction psychiatry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Affective neuroscience research has revealed that reward contains separable components of 'liking', 'wanting', and learning. Here we focus on current 'liking' and 'wanting' findings and applications to clinical disorders. 'Liking' is the hedonic impact derived from a pleasant experience, and is amplified by opioid and related signals in discrete sites located in limbic-related brain areas. 'Wanting' refers to incentive salience, a motivation process for reward, and is mediated by larger systems involving mesocorticolimbic dopamine. Deficits in incentive salience may contribute to avolitional features of depression and related disorders, whereas deficits in hedonic impact may produce true anhedonia. Excesses in incentive salience, on the other hand, can lead to addiction, especially when narrowly focused on a particular target. Finally, a fearful form of motivational salience may even contribute to some paranoia symptoms of schizophrenia and related disorders.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.