Evidence map›Paper›PMID 29503634›Full record

ArticleFrontiers in microbiology2018

Excision of Nucleopolyhedrovirus Form Transgenic Silkworm Using the CRISPR/Cas9 System.

Zhanqi Dong, Feifan Dong, Xinbo Yu, Liang Huang, Yaming Jiang, Zhigang Hu, Peng Chen, Cheng Lu, Minhui Pan

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. CRISPR/Cas12a Mediated Genome Editing EnhancesFrontiers in bioengineering and biotechnology · 2020
    Article
  6. CRISPR Disruption ofInsects · 2019
    Article
  7. Article
  8. Efficient Genome Editing ofFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhanqi DongState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Feifan DongState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Xinbo YuCollege of Biotechnology, Southwest University, Chongqing, China.
Liang HuangState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Yaming JiangState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Zhigang HuState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Peng ChenState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Cheng LuState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.
Minhui PanState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CRISPR/Cas9-mediated genome engineering has been shown to efficiently suppress infection by disrupting genes of the pathogen. We recently constructed transgenic lines expressing CRISPR/Cas9 and the double sgRNA target

Indexed as

antiviral therapyBmNPVBombyx moriCRISPR/Cas9transgenic

Identifiers

PMID29503634
PMCPMC5820291

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.