Evidence map›Paper›PMID 29502430›Full record

ArticleAIDS care2018

Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England.

Marthe Le Prevost, Alejandro Arenas-Pinto, Diane Melvin, Francesca Parrott, Caroline Foster, Deborah Ford, Michael Evangeli, Alan Winston, Kate Sturgeon, Katie Rowson and 3 more

Open access · hybridAbstract read
In one paragraph

Article in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Aging of adult lifetime survivors with perinatal HIV.Current opinion in HIV and AIDS · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Peritransition Outcomes of Southeast Asian Adolescents and Young Adults With HIV Transferring From Pediatric to Adult Care.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Marthe Le Prevosta MRC Clinical Trials Unit at UCL , University College London , London , UK.
Alejandro Arenas-Pintoa MRC Clinical Trials Unit at UCL , University College London , London , UK.
Diane Melvinb Department of Psychology , Imperial College Healthcare NHS Trust , London , UK.
Francesca Parrotta MRC Clinical Trials Unit at UCL , University College London , London , UK.
Caroline Fosterc The Family and 900 Clinics , Imperial College Healthcare NHS Trust , London , UK.
Deborah Forda MRC Clinical Trials Unit at UCL , University College London , London , UK.
Michael Evangelid Department of Psychology , Royal Holloway University of London , Surrey , UK.
Alan Winstone Section of Retrovirology , Imperial College London , London , UK.
Kate Sturgeona MRC Clinical Trials Unit at UCL , University College London , London , UK.
Katie Rowsona MRC Clinical Trials Unit at UCL , University College London , London , UK.
Diana M Gibba MRC Clinical Trials Unit at UCL , University College London , London , UK.
Ali Judda MRC Clinical Trials Unit at UCL , University College London , London , UK.
Adolescents and Adults Living with Perinatal HIV (AALPHI) Steering Committeea MRC Clinical Trials Unit at UCL , University College London , London , UK.
MRC Clinical Trials Unit at UCL · GBImperial College Healthcare NHS Trust · GBUniversity College London · GBImperial College London · GBRoyal Holloway University of London · GB

Funding

Medical Research Council MC_UU_12023/26
6 · The paper itself

Abstract

Adolescents with perinatal HIV (PHIV) may be at higher risk of anxiety and depression than HIV negative young people. We investigated prevalence of anxiety and depression symptoms in 283 PHIV and 96 HIV-affected (HIV-negative) young people in England recruited into the Adolescents and Adults Living with Perinatal HIV (AALPHI) cohort. We used Hospital Anxiety and Depression Scale (HADS) scores and linear regression investigated predictors of higher (worse) scores.115 (41%) and 29 (30%) PHIV and HIV-affected young people were male, median age was 16 [interquartile range 15,18] and 16 [14,18] years and 241 (85%) and 71 (74%) were black African, respectively. There were no differences in anxiety and depression scores between PHIV and HIV-affected participants. Predictors of higher anxiety scores were a higher number of carers in childhood, speaking a language other than English at home, lower self-esteem, ever thinking life was not worth living and lower social functioning. Predictors of higher depression scores were male sex, death of one/both parents, school exclusion, lower self-esteem and lower social functioning. In conclusion, HIV status was not associated with anxiety or depression scores, but findings highlight the need to identify and support young people at higher risk of anxiety and depression.

Indexed as

AdolescentAdultAnxietyCaregiversChildCohort StudiesDepressionEnglandFemaleHIV InfectionsHumansMalePregnancySelf ConceptYoung AdultAnxietydepressionHIVperinatalyoung people

Identifiers

PMID29502430
PMCPMC5989154
OpenAlexW2793181764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.