Evidence map›Paper›PMID 29502307›Full record

ReviewCancer microenvironment : official journal of the International Cancer Microenvironment Society2018

Role of the Nervous System in Tumor Angiogenesis.

Nyanbol Kuol, Lily Stojanovska, Vasso Apostolopoulos, Kulmira Nurgali

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer microenvironment : official journal of the International Cancer Microenvironment Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Cancer and neurotransmitter receptors.Chinese medical journal · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. The tumor-nerve circuit in breast cancer.Cancer metastasis reviews · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nyanbol KuolCentre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Australia.
Lily StojanovskaCentre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Australia.
Vasso ApostolopoulosCentre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Australia.
Kulmira NurgaliCentre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Australia. Kulmira.Nurgali@vu.edu.au.ORCID http://orcid.org/0000-0002-2597-6929
Victoria University · AUWestern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of cancer involves an intricate process, wherein many identified and unidentified factors play a role. Tumor angiogenesis, growth of new blood vessels, is one of the major prerequisites for tumor growth as tumor cells rely on adequate oxygen and nutrient supply as well as the removal of waste products. Growth factors including VEGF orchestrate the development of angiogenesis. In addition, nervous system via the release of neurotransmitters contributes to tumor angiogenesis. The nervous system governs functional activities of many organs, and, as tumors are not independent organs within an organism, this system is integrally involved in tumor growth and progression via regulating tumor angiogenesis. Various neurotransmitters have been reported to play an important role in tumor angiogenesis.

Indexed as

AngiogenesisCancerNervous systemNeuro-cancer interactionNeuropeptidesNeurotransmitters

Identifiers

PMID29502307
PMCPMC6008269
OpenAlexW2791950331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.