Evidence map›Paper›PMID 29501837›Full record

ArticlePhysiology & behavior2018

Dietary influences on cognition.

A C Reichelt, L E Stoeckel, L P Reagan, C A Winstanley, K A Page

Open access · greenAbstract read
In one paragraph

Article in Physiology & behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Is there a role for higher cognitive processes in the development of obesity in humans?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  12. Article
  13. Review
  14. Facets of Impulsivity in Relation to Diet Quality and Physical Activity in Adolescence.International journal of environmental research and public health · 2021
    Article
  15. Glucose, Fructose, and Urate Transporters in the Choroid Plexus Epithelium.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

A C ReicheltSchool of Health and Biomedical Science, RMIT University, Melbourne, Victoria 3083, Australia.
L E StoeckelNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
L P ReaganDepartment of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA; W.J.B. Dorn Veterans Affairs Hospital, Columbia, SC 29208, USA. Electronic address: Lawrence.Reagan@uscmed.sc.edu.
C A WinstanleyDepartment of Psychology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada.
K A PageDepartment of Internal Medicine, Division of Endocrinology, Keck School of Medicine University of Southern California, Los Angeles, CA, USA.
National Institutes of Health · USRMIT University · AUUniversity of British Columbia · CAUniversity of South Carolina · USUniversity of Southern California · US

Funding

Neural Mechanisms for Appetitive Responses to High Reward FoodsR01DK102794 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PAGE, KATHLEEN ALANNA · 2016 to 2020
$2.7M
Decreased CNS leptin activity in co-morbid depression and obesityI01BX001804 · VA · VETERANS HEALTH ADMINISTRATION · PI REAGAN, LAWRENCE P · 2013 to 2021
–
Immune basis for hippocampal cholinerginc deficits in pyridostigmine-treated ratsI01BX002664 · VA · VETERANS HEALTH ADMINISTRATION · PI LAWRENCE P REAGAN · 2015 to 2026
–
BLRD VA I01 BX001804BLRD VA I01 BX002664NIDDK NIH HHS R01 DK102794
6 · The paper itself

Abstract

Obesity is a world-wide crisis with profound healthcare and socio-economic implications and it is now clear that the central nervous system (CNS) is a target for the complications of metabolic disorders like obesity. In addition to decreases in physical activity and sedentary lifestyles, diet is proposed to be an important contributor to the etiology and progression of obesity. Unfortunately, there are gaps in our knowledge base related to how dietary choices impact the structural and functional integrity of the CNS. For example, while chronic consumption of hypercaloric diets (increased sugars and fat) contribute to increases in body weight and adiposity characteristic of metabolic disorders, the mechanistic basis for neurocognitive deficits in obesity remains to be determined. In addition, studies indicate that acute consumption of hypercaloric diets impairs performance in a wide variety of cognitive domains, even in normal non-obese control subjects. These results from the clinical and basic science literature indicate that diet can have rapid, as well as long lasting effects on cognitive function. This review summarizes our symposium at the 2017 Society for the Study of Ingestive Behavior (SSIB) meeting that discussed these effects of diet on cognition. Collectively, this review highlights the need for integrated and comprehensive approaches to more fully determine how diet impacts behavior and cognition under physiological conditions and in metabolic disorders like type 2 diabetes mellitus (T2DM) and obesity.

Indexed as

AnimalsCognitionCognitive DysfunctionCongresses as TopicDietHumansDementiaDiabetesFructoseImpassivityInsulinObesity

Identifiers

PMID29501837
PMCPMC6071323
OpenAlexW2790680355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.