Evidence map›Paper›PMID 29501026›Full record

ReviewCurrent opinion in cell biology2018

Subcellular scaling: does size matter for cell division?

Rebecca Heald, Romain Gibeaux

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Organelle size scaling over embryonic development.Wiley interdisciplinary reviews. Developmental biology · 2020
    Review
  8. Article
  9. Emergent properties of mitotic chromosomes.Current opinion in cell biology · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rebecca HealdDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Electronic address: bheald@berkeley.edu.
Romain GibeauxDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Electronic address: romain.gibeaux@univ-rennes1.fr.

Funding

Mechanisms of mitosis and size control in XenopusR35GM118183 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALD, REBECCA W · 2016 to 2025
$8.2M
NIGMS NIH HHS R35 GM118183
6 · The paper itself

Abstract

Among different species or cell types, or during early embryonic cell divisions that occur in the absence of cell growth, the size of subcellular structures, including the nucleus, chromosomes, and mitotic spindle, scale with cell size. Maintaining correct subcellular scales is thought to be important for many cellular processes and, in particular, for mitosis. In this review, we provide an update on nuclear and chromosome scaling mechanisms and their significance in metazoans, with a focus on Caenorhabditis elegans, Xenopus and mammalian systems, for which a common role for the Ran (Ras-related nuclear protein)-dependent nuclear transport system has emerged.

Indexed as

AnimalsCaenorhabditis elegansCell NucleusChromosomesMitosis

Identifiers

PMID29501026
PMCPMC5988940

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.