ArticleAddiction (Abingdon, England)2018
Associations between personality disorders and cannabis use and cannabis use disorder: a population-based twin study.
Article in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Change of substance-related hospitalisation in adolescents after cannabis legalisation in Thailand in 2022.Addiction (Abingdon, England) · 2026Article
- Identifying behavioral and biological predictors of cannabis vapor self-administration in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Psychological, social factors, and smoking behavior mediated the effects of cannabis use on personality disorders: A Mendelian randomization study.Frontiers in psychiatry · 2025Article
- The Co-occurrence of Personality Disorders and Substance Use Disorders.Current psychiatry reports · 2023Review
- An exploration of multivariate symptom clusters of cannabis use disorder in young adults.Addictive behaviors · 2022Article
- Self-reported perceived negative consequences of marijuana use among U.S. young adult users, 2008-2019.Addictive behaviors · 2022Article
- The Potential Impact of Recreational Cannabis Legalization on the Prevalence of Cannabis Use Disorder and Psychotic Disorders: A Retrospective Observational Study.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Observational
- Caffeine consumption, toxicity, tolerance and withdrawal; shared genetic influences with normative personality and personality disorder traits.Experimental and clinical psychopharmacology · 2021Article
- Total and cause-specific mortality in patients with personality disorders: the association between comorbid severe mental illness and substance use disorders.Social psychiatry and psychiatric epidemiology · 2021Article
- Cannabis Use, Cannabis Use Disorder, and Comorbid Psychiatric Illness: A Narrative Review.Journal of clinical medicine · 2020Review
- Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort.Translational psychiatry · 2020Article
- Testing Genetic and Environmental Associations Between Personality Disorders and Cocaine Use: A Population-Based Twin Study.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2018Article
- Criminalization Through Transinstitutionalization: A Critical Review of the Penrose Hypothesis in the Context of Compensation Imprisonment.Frontiers in psychiatry · 2018Article
- Borderline personality disorder and substance use disorders: an updated review.Borderline personality disorder and emotion dysregulation · 2018Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
BACKGROUND AND
aimsIndividual differences in DSM-IV personality disorders (PDs) are associated with increased prevalence of substance use disorders. Our aims were to determine which combination of PDs trait scores best predict cannabis use (CU) and cannabis use disorder (CUD), and to estimate the size and significance of genetic and environmental risks in PD traits shared with CU and CUD.
designLinear mixed-effects models were used to identify PD traits for inclusion in twin analyses to explore the genetic and environmental associations between the traits and cannabis use.
settingCross-sectional data were obtained from Norwegian adult twins in a face-to-face interview in 1999-2004 as part of a population-based study of mental health.
participantsSubjects were 1419 twins (μ MEASUREMENTS: PD traits were assessed using DSM-IV criteria. Life-time CU and CUD were based on DSM-IV abuse and dependence criteria, including withdrawal and craving.
findingsAfter adjusting for age and sex, antisocial [β = 0.23, 95% confidence interval (CI) = 0.19-0.28] and borderline PDs (β = 0.20, 95% CI = 0.14-0.26) were associated strongly with CU. Antisocial (β = 0.26, 95% CI = 0.21-0.31) and borderline PDs (β = 0.12, 95% CI = 0.06-0.18) were also linked strongly to CUD. Genetic risks in antisocial and borderline PD traits explained 32-60% of the total variance in CU and CUD. Dependent and avoidant PDs explained 11 and 16% of the total variance in CU and CUD, respectively.
conclusionsIndividual differences in the liability to cannabis use and cannabis use disorder appear to be linked to genetic risks correlated with antisocial and borderline personality disorder traits.
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