Evidence map›Paper›PMID 29500823›Full record

ArticleEuropean journal of immunology2018

Brain-resident memory CD8

Ilija Brizić, Božo Šušak, Maja Arapović, Peter C Huszthy, Lea Hiršl, Daria Kveštak, Vanda Juranić Lisnić, Mijo Golemac, Ester Pernjak Pugel, Jelena Tomac and 5 more

Open access · greenAbstract read
In one paragraph

Article in European journal of immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  4. Article
  5. Review
  6. bTInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  15. Review
  16. Article
  17. Innate lymphoid cells in neuroinflammation.Frontiers in cellular neuroscience · 2024
    Review
  18. Article
  19. Article
  20. Keeping T cell memories in mind.Trends in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 6 countries.

Ilija BrizićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Božo ŠušakDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Maja ArapovićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Peter C HuszthyDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Lea HiršlDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Daria KveštakDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Vanda Juranić LisnićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Mijo GolemacDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Ester Pernjak PugelDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Jelena TomacDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Annette OxeniusInstitute of Microbiology, ETH Zürich, Zürich, Switzerland.
William J BrittDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jurica ArapovićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Astrid KrmpotićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Stipan JonjićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.ORCID 0000-0001-5003-3108
University of Rijeka · HRUniversity of Mostar · BAETH Zurich · CHUniversity of Alabama at Birmingham · US

Funding

Congenital CMV and CNS Infection Mechanisms of Protective ImmunityR01AI089956 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI William Jarvis Britt · 2011 to 2026
$7.7M
NIAID NIH HHS R01 AI089956
6 · The paper itself

Abstract

Congenital HCMV infection is a leading infectious cause of long-term neurodevelopmental sequelae. Infection of newborn mice with mouse cytomegalovirus (MCMV) intraperitoneally is a well-established model of congenital human cytomegalovirus infection, which best recapitulates the hematogenous route of virus spread to brain and subsequent pathology. Here, we used this model to investigate the role, dynamics, and phenotype of CD8

Indexed as

Adoptive TransferAnimalsAnimals, NewbornBrainCD8-Positive T-LymphocytesCells, CulturedCongenital AbnormalitiesCytomegalovirusCytomegalovirus InfectionsDisease Models, AnimalHumansImmunologic MemoryMiceMice, Inbred C57BLMuromegalovirusT-Lymphocytes, CytotoxicBrain pathologyCongenital CMV infectionMicrogliaMouse cytomegalovirusTissue-resident memory T cells

Identifiers

PMID29500823
PMCPMC6422351
OpenAlexW2792697291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.