Evidence map›Paper›PMID 29500718›Full record

ArticleThe protein journal2018

Interaction Between a Gelsolin from Dendrorhynchus zhejiangensis with Three Gelsolin-Like Domains and Actin In Vitro.

Ye Li, Lei Chen, Jun Zhou, Xiurong Su, Taiwu Li

Abstract read
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In one paragraph

Article in The protein journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ye LiSchool of Marine Sciences, Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Lei ChenSchool of Marine Sciences, Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Jun ZhouSchool of Marine Sciences, Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Xiurong SuSchool of Marine Sciences, Ningbo University, Ningbo, Zhejiang, People's Republic of China. suxiurong@nbu.edu.cn.
Taiwu LiSchool of Marine Sciences, Ningbo University, Ningbo, Zhejiang, People's Republic of China.
Ningbo University · CN

Funding

Natural Science Foundation of China 31272637Natural Science Foundation of China 31402282
6 · The paper itself

Abstract

The gelsolin family proteins are best known for involvement in cytoskeletal rearrangement by controlling actin organization during a variety of cellular processes. Previously, a 1962 bp cDNA encoding a 41.7 kDa protein with three gelsolin-like domains (G domains) from Dendrorhynchus zhejiangensis was identified and named as DzGSN. In this study, the sequence and function of a novel member of the gelsolin family proteins from D. zhejiangensis have been analyzed. Sequence alignment indicates that DzGSN is highly homologous to human gelsolin (35% identity) and human CapG (36% identity). The important functional motifs and critical amino acids were identified. The nucleating- and severing-actin activities of recombinant DzGSN (rDzGSN) were then investigated by using atomic force microscopy in vitro. After incubation with rDzGSN in the presence of Ca

Indexed as

ActinsAmino Acid SequenceAnimalsEscherichia coliGelsolinHumansMicroscopy, Atomic ForceRecombinant ProteinsTwo-Hybrid System TechniquesActinsGelsolinRecombinant ProteinsActinAtomic force microscopyGelsolinNemerteanYeast two-hybrid system

Identifiers

PMID29500718
OpenAlexW2790481935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.