Evidence map›Paper›PMID 29500669›Full record

ArticlePflugers Archiv : European journal of physiology2018

The role of RyR2 oxidation in the blunted frequency-dependent facilitation of Ca

Elisa Bovo, Stefan R Mazurek, Aleksey V Zima

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Mitochondrial CaJournal of molecular and cellular cardiology · 2021
    Review
  8. RyR2 and Calcium Release in Heart Failure.Frontiers in physiology · 2021
    Review
  9. Article
  10. Novel approach for quantification of endoplasmic reticulum CaAmerican journal of physiology. Heart and circulatory physiology · 2019
    Article
  11. Oxidation of ryanodine receptor after ischemia-reperfusion increases propensity of CaAmerican journal of physiology. Heart and circulatory physiology · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elisa BovoDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL, 60153, USA.
Stefan R MazurekDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL, 60153, USA.
Aleksey V ZimaDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL, 60153, USA. azima@luc.edu.
Loyola University Chicago · US

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
Calcium release channel dysfunction: molecular mechanismsR01HL130231 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZIMA, ALEKSEY V · 2016 to 2019
$1.5M
Foundation for the National Institutes of Health HL130231NHLBI NIH HHS R01 HL130231NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

Defective Ca

Indexed as

Calcium SignalingOxidative StressAction PotentialsAnimalsCells, CulturedHeart FailureMyocytes, CardiacRabbitsRyanodine Receptor Calcium Release ChannelRyanodine Receptor Calcium Release ChannelCa2+ homeostasisHeart failureOxidative stressRyanodine receptorSarcoplasmic reticulumVentricular myocytes

Identifiers

PMID29500669
PMCPMC5948141
OpenAlexW2794273796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.