ArticleJournal of neuro-oncology2018
Allergic conditions and risk of glioma and meningioma in the CERENAT case-control study.
Article in Journal of neuro-oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- The association between allergy and risk of brain tumors: Evidence from 40 observational studies.Acta neurochirurgica · 2025Pooled it
- Eczema as a protective factor for brain cancer: a meta-analysis.BMC cancer · 2022Pooled it
- Noncutaneous and Cutaneous Cancer Risk in Patients With Atopic Dermatitis: A Systematic Review and Meta-analysis.JAMA dermatology · 2020Pooled it
- The relationship between asthma and glioma: a case-control study in a universal access healthcare system.Journal of neuro-oncology · 2026Article
- Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Proapoptotic and proautophagy effect of H1-receptor antagonist desloratadine in human glioblastoma cell lines.Medical oncology (Northwood, London, England) · 2023Article
- Prostate-Specific Membrane Antigen (PSMA) Expression in The Neovasculature of High Grade Gliomas (Histopathological and Immunohistochemical Study).Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Prevalence of autoimmunity and atopy in US adults with glioblastoma and meningioma.Neuro-oncology · 2022Article
- A decreased risk of meningioma in women smokers was only observed in American studies rather than studies conducted in other countries: a systematic review and meta-analysis.Chinese neurosurgical journal · 2021Article
- HLA polymorphisms and risk of glioblastoma in Koreans.PloS one · 2021Article
- Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma.Cancer medicine · 2020Article
- Multi-Omics Analysis in Initiation and Progression of Meningiomas: From Pathogenesis to Diagnosis.Frontiers in oncology · 2020Review
- Article
- Review
- MDM4 contributes to the increased risk of glioma susceptibility in Han Chinese population.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inverse association between allergic conditions and glioma risk has been consistently reported in epidemiological studies with little attention paid to potential environmental confounders; the association with meningioma risk is less consistent. We examined the association between allergy history and risk of glioma and meningioma in adults using data from the CERENAT (CEREbral tumors: a NATional study) multicenter case-control study carried out in 4 areas in France in 2004-2010. Participants' histories of doctor-diagnosed allergic asthma, eczema, rhinitis/hay fever and other allergic conditions were collected at onset through a detailed questionnaire delivered in a face-to-face interview. Conditional logistic regression for matched sets was adjusted for participants' educational level and mobile phone use. A total of 273 glioma cases, 218 meningioma cases and 982 matched controls selected from the local electoral rolls were analyzed. A significant inverse association was found between glioma and a history of any allergy (OR 0.52, 95% CI 0.36-0.75), with a dose-effect relationship with the number of allergic conditions reported (p-trend = 0.001) and a particularly strong association with hay fever/allergic rhinitis (OR 0.46, 95% CI 0.30-0.72). Interestingly, associations with glioma risk were more pronounced in women. For meningioma, no association was observed with overall or specific allergic conditions. Our findings confirmed the inverse association between allergic conditions and glioma risk but questioned the role of allergy in meningioma risk. Future research is needed to clarify the biological mechanism of overall allergy and allergic rhinitis on glioma and to confirm the different effect by gender.
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