ArticleEuropean journal of nuclear medicine and molecular imaging2018
Feasibility of state of the art PET/CT systems performance harmonisation.
Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.
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Who cites it
94 citing papers in PubMed, 1 synthesis or guideline pooled it.
- PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0.European journal of nuclear medicine and molecular imaging · 2023Guideline
- Repeatability of QuantitativeJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020Trial
- Improving the predictive value of end-of-treatment PET/ CT in diffuse large B-cell lymphoma.Haematologica · 2026Article
- Physiological uptake patterns of gastric lymph node stations onQuantitative imaging in medicine and surgery · 2026Article
- Multicenter comparison of radionuclide calibrators and SPECT/CT protocols for quantitativeEJNMMI physics · 2026Article
- Exploring the feasibility of a 40-minute uptake time for long axial field of view [European journal of nuclear medicine and molecular imaging · 2026Article
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- Critical review of partial volume correction methods in PET and SPECT imaging: benefits, pitfalls, challenges, and future outlook.European journal of nuclear medicine and molecular imaging · 2026Review
- Digital versus analogue PET in parathyroid imaging: comparison of PET metrics and machine learning-based characterisation of hyperfunctioning lesions (the DIGI-PET study).European journal of nuclear medicine and molecular imaging · 2026Article
- Clinical evaluation of tissue-dependent and spatially-variant positron range correction for Gallium-68 PET imaging.European journal of nuclear medicine and molecular imaging · 2026Article
- Lymph node disease in 2-deoxy-2-fluorodeoxyglucose positron emission tomography/computed tomography imaging: Advances in artificial intelligence-driven automatic segmentation and precise diagnosis.World journal of clinical oncology · 2025Review
- Standardization of PET/CT Performance Requirements for Whole-Body Quantitative Imaging: An International Proposal.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Review
- Impact of patient size on image quality of OSEM3D and BSREM reconstructions in [EJNMMI physics · 2025Article
- Effects of a deep learning-based image quality enhancement method on a digital-BGO PET/CT system forEJNMMI physics · 2025Article
- Improving image reconstruction to quantify dynamic whole-body PET/CT: Q.Clear versus OSEM.EJNMMI physics · 2025Article
- Article
- Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study.EJNMMI physics · 2025Article
- High concordance of PET-CT treatment response evaluation according to PERCIST 1.0 when comparing images reconstructed with OSEM vs. BSREM.Clinical physiology and functional imaging · 2025Article
- Pharmacokinetic analysis and simplified uptake measures for tumour lesion [European journal of nuclear medicine and molecular imaging · 2025Article
- [18F]FDG PET/CT to reduce the need for sentinel lymph node biopsy in early-stage oral cancer: PETN0-study protocol.PloS one · 2025Article
34 more citing papers are in PubMed but not listed here.
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7 authors.
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Abstract
purposeThe objective of this study was to explore the feasibility of harmonising performance for PET/CT systems equipped with time-of-flight (ToF) and resolution modelling/point spread function (PSF) technologies. A second aim was producing a working prototype of new harmonising criteria with higher contrast recoveries than current EARL standards using various SUV metrics.
methodsFour PET/CT systems with both ToF and PSF capabilities from three major vendors were used to acquire and reconstruct images of the NEMA NU2-2007 body phantom filled conforming EANM EARL guidelines. A total of 15 reconstruction parameter sets of varying pixel size, post filtering and reconstruction type, with three different acquisition durations were used to compare the quantitative performance of the systems. A target range for recovery curves was established such that it would accommodate the highest matching recoveries from all investigated systems. These updated criteria were validated on 18 additional scanners from 16 sites in order to demonstrate the scanners' ability to meet the new target range.
resultsEach of the four systems was found to be capable of producing harmonising reconstructions with similar recovery curves. The five reconstruction parameter sets producing harmonising results significantly increased SUVmean (25%) and SUVmax (26%) contrast recoveries compared with current EARL specifications. Additional prospective validation performed on 18 scanners from 16 EARL accredited sites demonstrated the feasibility of updated harmonising specifications. SUVpeak was found to significantly reduce the variability in quantitative results while producing lower recoveries in smaller (≤17 mm diameter) sphere sizes.
conclusionsHarmonising PET/CT systems with ToF and PSF technologies from different vendors was found to be feasible. The harmonisation of such systems would require an update to the current multicentre accreditation program EARL in order to accommodate higher recoveries. SUVpeak should be further investigated as a noise resistant alternative quantitative metric to SUVmax.
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