ArticleScientific reports2018
Essential oils and their components are a class of antifungals with potent vapour-phase-mediated anti-Candida activity.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The Potential of Plant Secondary Metabolites as Bread Mould Inhibitors: Exploring Their Individual and Combined Antifungal Effect.Foods (Basel, Switzerland) · 2025Article
- Potential Anti-Infectious Activity of Essential Oil Chemotypes ofPlants (Basel, Switzerland) · 2024Article
- Essential Oils ofFoods (Basel, Switzerland) · 2023Article
- Antifungal Potential of Some Herb Decoctions and Essential Oils onHealthcare (Basel, Switzerland) · 2022Article
- Antifungal and Anti-Virulent Activity ofMolecules (Basel, Switzerland) · 2022Article
- Using essential oils to overcome bacterial biofilm formation and their antimicrobial resistance.Saudi journal of biological sciences · 2021Review
- Microbial Interkingdom Biofilms and the Quest for Novel Therapeutic Strategies.Microorganisms · 2021Review
- Ethnopharmacology, Phytochemistry, and Pharmacological Properties ofEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Inhibitory Activity of Essential Oils againstMicroorganisms · 2020Article
- Striking essential oil: tapping into a largely unexplored source for drug discovery.Scientific reports · 2020Article
- Improved in vitro and in vivo Anti-International journal of nanomedicine · 2020Article
- Unusual and Highly Bioactive Sesterterpenes Synthesized byApplied and environmental microbiology · 2019Article
- Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents.Molecules (Basel, Switzerland) · 2018Article
- Chemical Composition and Antibacterial Activity of Essential Oils fromMolecules (Basel, Switzerland) · 2018Article
- Methodologies forMicrobial cell (Graz, Austria) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multi-resistant microorganisms continue to challenge medicine and fuel the search for new antimicrobials. Here we show that essential oils and their components are a promising class of antifungals that can have specific anti-Candida activity via their vapour-phase. We quantify the vapour-phase-mediated antimicrobial activity (VMAA) of 175 essential oils and 37 essential oil components, representing more than a 1,000 unique molecules, against C. albicans and C. glabrata in a novel vapour-phase-mediated susceptibility assay. Approximately half of the tested essential oils and their components show growth-inhibitory VMAA. Moreover, an average greater activity was observed against the intrinsically more resistant C. glabrata, with essential oil component citronellal having a highly significant differential VMAA. In contrast, representatives of each class of antifungals currently used in clinical practice showed no VMAA. The vapour-phase-mediated susceptibility assay presented here thus allows for the simple detection of VMAA and can advance the search for novel (applications of existing) antimicrobials. This study represents the first comprehensive characterisation of essential oils and their components as a unique class of antifungals with antimicrobial properties that differentiate them from existing antifungal classes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.