Evidence map›Paper›PMID 29500354›Full record

ArticleNature communications2018

CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.

Kevin W Huynh, Jiansen Jiang, Natalia Abuladze, Kirill Tsirulnikov, Liyo Kao, Xuesi Shao, Debra Newman, Rustam Azimov, Alexander Pushkin, Z Hong Zhou and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Inactivation mechanisms of NaCommunications biology · 2025
    Article
  10. Article
  11. Role of channels in the ObioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Current medicinal chemistry · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The role of NaPflugers Archiv : European journal of physiology · 2024
    Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kevin W HuynhDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Jiansen JiangCalifornia NanoSystems Institute, University of California, Los Angeles, CA, 90095, USA.
Natalia AbuladzeDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Kirill TsirulnikovDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Liyo KaoDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Xuesi ShaoDepartment of Neurobiology, University of California, Los Angeles, CA, 90095, USA.
Debra NewmanDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Rustam AzimovDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Alexander PushkinDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA. apushkin@mednet.ucla.edu.
Z Hong ZhouCalifornia NanoSystems Institute, University of California, Los Angeles, CA, 90095, USA. Hong.Zhou@ucla.edu.
Ira KurtzDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA. ikurtz@mednet.ucla.edu.

Funding

The Biology of NBCe1 in Health and DiseaseR01DK077162 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRA KURTZ · 2007 to 2026
$6.7M
Genome Structure, Transcription and Packaging of dsRNA VirusesR01AI094386 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2012 to 2026
$6.0M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
In situ atomic structures of the Kaposi's sarcoma-associated herpesvirus portal-terminase complex and glycoproteinsR01DE025567 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING, ZHOU, Z HONG · 2016 to 2024
$4.0M
Interdisciplinary Training in Virology and Gene TherapyT32AI060567 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING · 2004 to 2018
$3.4M
West/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
NEPHROLOGY SCIENTIST TRAINING GRANTT32DK007789 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURTZ, IRA · 2000 to 2017
$1.5M
NCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI094386NIAID NIH HHS T32 AI060567NIDCR NIH HHS R01 DE025567NIDDK NIH HHS R01 DK077162NIDDK NIH HHS T32 DK007789NIGMS NIH HHS R01 GM071940NIGMS NIH HHS U24 GM116792
6 · The paper itself

Abstract

Na

Indexed as

AcidsAlkaliesBiological TransportCryoelectron MicroscopyElectrophysiological PhenomenaHumansIon ExchangeIonsModels, MolecularSodiumSodium-Bicarbonate SymportersAcidsAlkaliesIonsSLC4A4 protein, humanSodiumSodium-Bicarbonate Symporters

Identifiers

PMID29500354
PMCPMC5834491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.