Evidence map›Paper›PMID 29500331›Full record

ArticleAging2018

Taking a HIF pill for old age diseases?

Stefan Kaluz, Chalet Tan, Erwin G Van Meir

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Hypoxia Pathway in Osteoporosis: Laboratory Data for Clinical Prospects.International journal of environmental research and public health · 2023
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stefan KaluzDepartment of Neurosurgery, Emory University, Atlanta, GA 30322, USA.
Chalet TanDepartment of Pharmaceutics and Drug Delivery, University of Mississippi, Oxford, MS 38677, USA.
Erwin G Van MeirDepartment of Neurosurgery, Emory University, Atlanta, GA 30322, USA.

Funding

Mechanisms of Action for KCN1 in the Control of Uveal Melanoma MetastasisR01CA176001 · NCI · EMORY UNIVERSITY · PI GROSSNIKLAUS, HANS E., VAN MEIR, ERWIN G. · 2014 to 2018
$1.7M
Discovery of chemical probes for uveal melanomaR01CA180805 · NCI · EMORY UNIVERSITY · PI GROSSNIKLAUS, HANS E., VAN MEIR, ERWIN G. · 2013 to 2015
$1.6M
NCI NIH HHS R01 CA176001NCI NIH HHS R01 CA180805
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsCardiovascular DiseasesGene Expression RegulationHumansHypoxia-Inducible Factor 1NeoplasmsOsteoarthritisOsteoporosisOxygenOxygen ConsumptionRetinal DiseasesHypoxia-Inducible Factor 1Oxygenarthritisatherosclerosis and cardiovascular diseasecancerhypoxiahypoxia-inducible factorosteoporosisretinal pathologies

Identifiers

PMID29500331
PMCPMC5892688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.